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GO:0043234 protein complex

Term Information

ID GO:0043234
Name protein complex
Ontology Cellular Component
Definition A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
Comment A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.
GONUTS GO:0043234 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact protein-protein complex

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_chembl309
goslim_pir456
goslim_generic149

Protein complexes

Database ID Name
IntAct atg12-atg5_mouse Atg12-Atg5 complex
IntAct atg17-atg29-atg31_yeast Atg17-Atg31-Atg29 complex
IntAct hipba_ecoli HipBA toxin-antitoxin complex
IntAct atg2-18_yeast ATG2-ATG18 complex
IntAct atg12-atg5_yeast ATG12-ATG5 complex

Cross-references

Database ID
Wikipedia Protein_complex

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043234:
Relationship To GO:0043234 Child Term Child Term Name
Is a GO:0002102 podosome
Is a GO:0031209 SCAR complex
Is a GO:0072379 ER membrane insertion complex
Is a GO:0070390 transcription export complex 2
Is a GO:0032039 integrator complex
Is a GO:0001535 radial spoke head
Is a GO:0001536 radial spoke stalk
Is a GO:0005839 proteasome core complex
Is a GO:0031105 septin complex
Is a GO:0031389 Rad17 RFC-like complex
Is a GO:0031390 Ctf18 RFC-like complex
Is a GO:0031391 Elg1 RFC-like complex
Is a GO:0031395 bursicon neuropeptide hormone complex
Is a GO:0089713 Cbf1-Met4-Met28 complex
Is a GO:0031431 Dbf4-dependent protein kinase complex
Is a GO:0032797 SMN complex
Is a GO:0043684 type IV secretion system complex
Is a GO:1990597 AIP1-IRE1 complex
Is a GO:0071159 NF-kappaB complex
Is a GO:0070421 DNA ligase III-XRCC1 complex
Is a GO:0034270 CVT complex
Is a GO:0034274 Atg12-Atg5-Atg16 complex
Is a GO:0032116 SMC loading complex
Is a GO:0043529 GET complex
Is a GO:0031074 nucleocytoplasmic shuttling complex
Is a GO:0009337 sulfite reductase complex (NADPH)
Is a GO:0071178 MAML2-RBP-Jkappa-ICN4 complex
Is a GO:0071179 MAML3-RBP-Jkappa-ICN1 complex
Is a GO:0031082 BLOC complex
Is a GO:0043291 RAVE complex
Is a GO:0031251 PAN complex
Is a GO:0005954 calcium- and calmodulin-dependent protein kinase complex
Is a GO:0017101 aminoacyl-tRNA synthetase multienzyme complex
Is a GO:1990565 HSP90-CDC37 chaperone complex
Is a GO:0046798 viral portal complex
Is a GO:0046806 viral scaffold
Is a GO:0043293 apoptosome
Is a GO:0071175 MAML2-RBP-Jkappa-ICN1 complex
Is a GO:0071176 MAML2-RBP-Jkappa-ICN2 complex
Is a GO:0071177 MAML2-RBP-Jkappa-ICN3 complex
Is a GO:0017177 glucosidase II complex
Is a GO:0034715 pICln-Sm protein complex
Is a GO:0034716 Gemin3-Gemin4-Gemin5 complex
Is a GO:0034717 Gemin6-Gemin7-unrip complex
Is a GO:0034718 SMN-Gemin2 complex
Is a GO:0034719 SMN-Sm protein complex
Is a GO:0070422 G-protein beta/gamma-Raf-1 complex
Is a GO:0035301 Hedgehog signaling complex
Is a GO:0008074 guanylate cyclase complex, soluble
Is a GO:0031262 Ndc80 complex
Is a GO:0071817 MMXD complex
Is a GO:0071819 DUBm complex
Is a GO:0071821 FANCM-MHF complex
Is a GO:0005838 proteasome regulatory particle
Is a GO:0008540 proteasome regulatory particle, base subcomplex
Is a GO:0008541 proteasome regulatory particle, lid subcomplex
Is a GO:0031931 TORC1 complex
Is a GO:0031932 TORC2 complex
Is a GO:0031250 anaerobic ribonucleoside-triphosphate reductase complex
Is a GO:0005577 fibrinogen complex
Is a GO:0005601 classical-complement-pathway C3/C5 convertase complex
Is a GO:0005602 complement component C1 complex
Is a GO:0005616 larval serum protein complex
Is a GO:0030314 junctional membrane complex
Is a GO:0043493 viral terminase complex
Is a GO:0048180 activin complex
Is a GO:0070310 ATR-ATRIP complex
Is a GO:0008278 cohesin complex
Is a GO:0008290 F-actin capping protein complex
Is a GO:0008537 proteasome activator complex
Is a GO:0009340 DNA topoisomerase IV complex
Is a GO:0009346 citrate lyase complex
Is a GO:0009366 enterobactin synthetase complex
Is a GO:0009368 endopeptidase Clp complex
Is a GO:0015627 type II protein secretion system complex
Is a GO:0016272 prefoldin complex
Is a GO:0016281 eukaryotic translation initiation factor 4F complex
Is a GO:0016465 chaperonin ATPase complex
Is a GO:0018444 translation release factor complex
Is a GO:0019035 viral integration complex
Is a GO:0019036 viral transcriptional complex
Is a GO:0019197 phosphoenolpyruvate-dependent sugar phosphotransferase complex
Is a GO:0019814 immunoglobulin complex
Is a GO:0030076 light-harvesting complex
Is a GO:0030080 B875 antenna complex
Is a GO:0030081 B800-820 antenna complex
Is a GO:0030082 B800-850 antenna complex
Is a GO:0030256 type I protein secretion system complex
Is a GO:0030257 type III protein secretion system complex
Is a GO:0030689 Noc complex
Is a GO:0030870 Mre11 complex
Is a GO:0030877 beta-catenin destruction complex
Is a GO:0030895 apolipoprotein B mRNA editing enzyme complex
Is a GO:0030896 checkpoint clamp complex
Is a GO:0030915 Smc5-Smc6 complex
Is a GO:0030929 ADPG pyrophosphorylase complex
Is a GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex
Is a GO:0030990 intraciliary transport particle
Is a GO:0030993 axonemal heterotrimeric kinesin-II complex
Is a GO:0035145 exon-exon junction complex
Is a GO:0042272 nuclear RNA export factor complex
Is a GO:0042555 MCM complex
Is a GO:0045239 tricarboxylic acid cycle enzyme complex
Is a GO:0045251 electron transfer flavoprotein complex
Is a GO:1990315 Mcs4 RR-MAPKKK complex
Is a GO:0045293 mRNA editing complex
Is a GO:0045298 tubulin complex
Is a GO:0005875 microtubule associated complex
Is a GO:0043256 laminin complex
Is a GO:1990345 MTREC complex
Is a GO:0031298 replication fork protection complex
Is a GO:0031422 RecQ helicase-Topo III complex
Is a GO:0016459 myosin complex
Is a GO:0043845 DNA polymerase III, proofreading complex
Is a GO:0043846 DNA polymerase III, clamp loader complex
Is a GO:0043847 DNA polymerase III, clamp loader chi/psi subcomplex
Is a GO:0043850 RecFOR complex
Is a GO:0070313 RGS6-DNMT1-DMAP1 complex
Is a GO:0031941 filamentous actin
Is a GO:0097495 H-NS-Hha complex
Is a GO:0000133 polarisome
Is a GO:0000346 transcription export complex
Is a GO:0000347 THO complex
Is a GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
Is a GO:0000797 condensin core heterodimer
Is a GO:0000808 origin recognition complex
Is a GO:0000930 gamma-tubulin complex
Is a GO:0001534 radial spoke
Is a GO:0005662 DNA replication factor A complex
Is a GO:0005663 DNA replication factor C complex
Is a GO:0005667 transcription factor complex
Is a GO:0005731 nucleolus organizer region
Is a GO:0005831 steroid hormone aporeceptor complex
Is a GO:0005832 chaperonin-containing T-complex
Is a GO:0005833 hemoglobin complex
Is a GO:0005835 fatty acid synthase complex
Is a GO:0005849 mRNA cleavage factor complex
Is a GO:0005850 eukaryotic translation initiation factor 2 complex
Is a GO:0005851 eukaryotic translation initiation factor 2B complex
Is a GO:0005852 eukaryotic translation initiation factor 3 complex
Is a GO:0005853 eukaryotic translation elongation factor 1 complex
Is a GO:0005854 nascent polypeptide-associated complex
Is a GO:0005861 troponin complex
Is a GO:0005885 Arp2/3 protein complex
Is a GO:0005931 axonemal nexin link
Is a GO:0005956 protein kinase CK2 complex
Is a GO:0008023 transcription elongation factor complex
Is a GO:0008180 COP9 signalosome
Is a GO:0032807 DNA ligase IV complex
Is a GO:0032449 CBM complex
Is a GO:0031499 TRAMP complex
Is a GO:0031511 Mis6-Sim4 complex
Is a GO:0031518 CBF3 complex
Is a GO:0031519 PcG protein complex
Is a GO:0031521 spitzenkorper
Is a GO:0031522 cell envelope Sec protein transport complex
Is a GO:0031523 Myb complex
Is a GO:0032045 guanyl-nucleotide exchange factor complex
Is a GO:0031617 NMS complex
Is a GO:0043511 inhibin complex
Is a GO:0043514 interleukin-12 complex
Is a GO:0043564 Ku70:Ku80 complex
Is a GO:0090443 FAR/SIN/STRIPAK complex
Is a GO:0043240 Fanconi anaemia nuclear complex
Is a GO:0002096 polkadots
Is a GO:0033593 BRCA2-MAGE-D1 complex
Is a GO:0033596 TSC1-TSC2 complex
Is a GO:0033597 mitotic checkpoint complex
Is a GO:0089701 U2AF
Is a GO:0033607 SOD1-Bcl-2 complex
Is a GO:0032517 SOD1-calcineurin complex
Is a GO:0071180 MAML3-RBP-Jkappa-ICN2 complex
Is a GO:0019773 proteasome core complex, alpha-subunit complex
Is a GO:0019774 proteasome core complex, beta-subunit complex
Is a GO:0030015 CCR4-NOT core complex
Is a GO:0010316 pyrophosphate-dependent phosphofructokinase complex
Is a GO:0032996 Bcl3-Bcl10 complex
Is a GO:0071181 MAML3-RBP-Jkappa-ICN3 complex
Is a GO:0071182 MAML3-RBP-Jkappa-ICN4 complex
Is a GO:0032766 NHE3/E3KARP/ACTN4 complex
Is a GO:0034064 Tor2-Mei2-Ste11 complex
Is a GO:1990526 Ste12p-Dig1p-Dig2p complex
Is a GO:1990527 Tec1p-Ste12p-Dig1p complex
Is a GO:1990528 Rvs161p-Rvs167p complex
Is a GO:1990530 Cdc50p-Drs2p complex
Is a GO:0030991 intraciliary transport particle A
Is a GO:0030992 intraciliary transport particle B
Is a GO:0097078 FAL1-SGD1 complex
Is a GO:0000817 COMA complex
Is a GO:0000939 condensed chromosome inner kinetochore
Is a GO:0000940 condensed chromosome outer kinetochore
Is a GO:0033557 Slx1-Slx4 complex
Is a GO:0070274 RES complex
Is a GO:0002142 stereocilia ankle link complex
Is a GO:0002144 cytosolic tRNA wobble base thiouridylase complex
Is a GO:0070876 SOSS complex
Is a GO:0097452 GAIT complex
Is a GO:0033104 type VI protein secretion system complex
Is a GO:0033061 DNA recombinase mediator complex
Is a GO:0033193 Lsd1/2 complex
Is a GO:0016592 mediator complex
Is a GO:0033551 monopolin complex
Is a GO:0010317 pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex
Is a GO:0010318 pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex
Is a GO:0000408 EKC/KEOPS complex
Is a GO:0032299 ribonuclease H2 complex
Is a GO:0070937 CRD-mediated mRNA stability complex
Is a GO:0000444 MIS12/MIND type complex
Is a GO:0009356 aminodeoxychorismate synthase complex
Is a GO:0048476 Holliday junction resolvase complex
Is a GO:0033254 vacuolar transporter chaperone complex
Is a GO:0033256 I-kappaB/NF-kappaB complex
Is a GO:0034973 Sid2-Mob1 complex
Is a GO:0034974 Swi5-Swi2 complex
Is a GO:0034977 ABIN2-NFKB1-MAP3K8 complex
Is a GO:0034978 PDX1-PBX1b-MRG1 complex
Is a GO:0034993 LINC complex
Is a GO:0034996 RasGAP-Fyn-Lyn-Yes complex
Is a GO:0000974 Prp19 complex
Is a GO:0071075 CUGBP1-eIF2 complex
Is a GO:0017102 methionyl glutamyl tRNA synthetase complex
Is a GO:0019008 molybdopterin synthase complex
Is a GO:0022623 proteasome-activating nucleotidase complex
Is a GO:0022624 proteasome accessory complex
Is a GO:0009327 NAD(P)+ transhydrogenase complex (AB-specific)
Is a GO:0034663 endoplasmic reticulum chaperone complex
Is a GO:0034664 Ig heavy chain-bound endoplasmic reticulum chaperone complex
Is a GO:0070516 CAK-ERCC2 complex
Is a GO:0070517 DNA replication factor C core complex
Is a GO:0034692 E.F.G complex
Is a GO:0070441 G-protein beta/gamma-Btk complex
Is a GO:0034657 GID complex
Is a GO:0071141 SMAD protein complex
Is a GO:0071147 TEAD-2 multiprotein complex
Is a GO:0071152 G-protein alpha(q)-synembrin complex
Is a GO:0071153 G-protein alpha(o)-synembrin complex
Is a GO:0071154 G-protein alpha(i)1-synembrin complex
Is a GO:0071155 G-protein alpha(13)-synembrin complex
Is a GO:0002111 BRCA2-BRAF35 complex
Is a GO:0070069 cytochrome complex
Is a GO:0070545 PeBoW complex
Is a GO:0002167 VRK3/VHR/ERK complex
Is a GO:1990615 Kelch-containing formin regulatory complex
Is a GO:1990622 CHOP-ATF3 complex
Is a GO:0032311 angiogenin-PRI complex
Is a GO:0071664 catenin-TCF7L2 complex
Is a GO:0035859 Seh1-associated complex
Is a GO:0070331 CD20-Lck-Fyn complex
Is a GO:0070332 CD20-Lck-Lyn-Fyn complex
Is a GO:0031838 haptoglobin-hemoglobin complex
Is a GO:0070552 BRISC complex
Is a GO:0070557 PCNA-p21 complex
Is a GO:0070559 lysosomal multienzyme complex
Is a GO:1990346 BID-BCL-xl complex
Is a GO:0071521 Cdc42 GTPase complex
Is a GO:0034044 exomer complex
Is a GO:0070385 egasyn-beta-glucuronidase complex
Is a GO:0070850 TACC/TOG complex
Is a GO:0000776 kinetochore
Is a GO:0034099 luminal surveillance complex
Is a GO:0071203 WASH complex
Is a GO:0070353 GATA1-TAL1-TCF3-Lmo2 complex
Is a GO:0070354 GATA2-TAL1-TCF3-Lmo2 complex
Is a GO:0002133 polycystin complex
Is a GO:0002929 MECO complex
Is a GO:0070214 CSK-GAP-A.p62 complex
Is a GO:0071563 Myo2p-Vac17p-Vac8p transport complex
Is a GO:0033588 Elongator holoenzyme complex
Is a GO:0034455 t-UTP complex
Is a GO:0034456 UTP-C complex
Is a GO:0034457 Mpp10 complex
Is a GO:0034464 BBSome
Is a GO:0032545 CURI complex
Is a GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)
Is a GO:0009344 nitrite reductase complex [NAD(P)H]
Is a GO:0031680 G-protein beta/gamma-subunit complex
Is a GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
Is a GO:0097071 interferon regulatory factor complex
Is a GO:0034741 APC-tubulin-IQGAP1 complex
Is a GO:0034743 APC-IQGAP complex
Is a GO:0034744 APC-IQGAP1-Cdc42 complex
Is a GO:0034745 APC-IQGAP1-Rac1 complex
Is a GO:0034746 APC-IQGAP1-CLIP-170 complex
Is a GO:0034748 Par3-APC-KIF3A complex
Is a GO:0034749 Scrib-APC complex
Is a GO:0034750 Scrib-APC-beta-catenin complex
Is a GO:0070531 BRCA1-A complex
Is a GO:0070532 BRCA1-B complex
Is a GO:0070533 BRCA1-C complex
Is a GO:1990586 divisome complex
Is a GO:0070467 RC-1 DNA recombination complex
Is a GO:0097076 transforming growth factor beta activated kinase 1 complex
Is a GO:0070693 P-TEFb-cap methyltransferase complex
Is a GO:0070695 FHF complex
Is a GO:0070767 BRCA1-Rad51 complex
Is a GO:0070826 paraferritin complex
Is a GO:0070288 ferritin complex
Is a GO:0070743 interleukin-23 complex
Is a GO:0070744 interleukin-27 complex
Is a GO:0070745 interleukin-35 complex
Is a GO:0098654 CENP-A recruiting complex
Is a GO:0044796 DNA polymerase processivity factor complex
Is a GO:0098733 hemidesmosome associated protein complex
Is a GO:1990469 Rhino-Deadlock-Cutoff Complex
Is a GO:0097619 PTEX complex
Is a GO:1990423 RZZ complex
Is a GO:1990630 IRE1-RACK1-PP2A complex
Is a GO:1990726 Lsm1-7-Pat1 complex
Is a GO:1990727 tubulin folding cofactor complex
Is a GO:0034081 polyketide synthase complex
Is a GO:0055087 Ski complex
Is a GO:0098561 methyl accepting chemotaxis protein complex
Is a GO:0005581 collagen trimer
Is a GO:0002199 zona pellucida receptor complex
Is a GO:1990130 Iml1 complex
Is a GO:1990131 Gtr1-Gtr2 GTPase complex
Is a GO:1990251 Mmi1 nuclear focus complex
Is a GO:1990477 NURS complex
Is a GO:0035649 Nrd1 complex
Is a GO:0097255 R2TP complex
Is a GO:0097373 MCM core complex
Is a GO:0098644 complex of collagen trimers
Is a GO:1990453 nucleosome disassembly/reassembly complex
Is a GO:0039658 TBK1-IKKE-DDX3 complex
Is a GO:1990078 replication inhibiting complex
Is a GO:1990499 raps-insc complex
Is a GO:1990509 PYM-mago-Y14 complex
Is a GO:1990252 Syp1 complex
Is a GO:1990296 scaffoldin complex
Is a GO:1990298 bub1-bub3 complex
Is a GO:1990706 MAD1 complex
Is a GO:1990730 VCP-NSFL1C complex
Is a GO:0002193 MAML1-RBP-Jkappa- ICN1 complex
Is a GO:0005643 nuclear pore
Is a GO:1990455 PTEN phosphatase complex
Is a GO:1990520 separase-securin complex
Is a GO:1990529 glycosylphosphatidylinositol-mannosyltransferase I complex
Is a GO:1990531 Lem3p-Dnf1p complex
Is a GO:1990662 S100A9 complex
Is a GO:1990724 galectin complex
Is a GO:1904564 Nbp35-Cfd1 ATPase complex
Is a GO:1905540 interleukin-7 receptor complex
Is a GO:0036286 eisosome filament
Is a GO:0044816 Nsk1-Dlc1 complex
Is a GO:0038059 IKKalpha-IKKalpha complex
Is a GO:1990356 sumoylated E2 ligase complex
Is a GO:0061696 pituitary gonadotropin complex
Is a GO:0061700 GATOR2 complex
Is a GO:0061702 inflammasome complex
Is a GO:0061703 pyroptosome complex
Is a GO:0098796 membrane protein complex
Is a GO:0098798 mitochondrial protein complex
Is a GO:0000109 nucleotide-excision repair complex
Is a GO:0000145 exocyst
Is a GO:0000307 cyclin-dependent protein kinase holoenzyme complex
Is a GO:0000502 proteasome complex
Is a GO:0000796 condensin complex
Is a GO:0000938 GARP complex
Is a GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex
Is a GO:0097537 Y-shaped link
Is a GO:0097539 ciliary transition fiber
Is a GO:0009336 sulfate adenylyltransferase complex (ATP)
Is a GO:0017119 Golgi transport complex
Is a GO:0030008 TRAPP complex
Is a GO:0031371 ubiquitin conjugating enzyme complex
Is a GO:0031588 nucleotide-activated protein kinase complex
Is a GO:0032300 mismatch repair complex
Is a GO:0032806 carboxy-terminal domain protein kinase complex
Is a GO:0033263 CORVET complex
Is a GO:0034519 cytoplasmic RNA cap binding complex
Is a GO:0035267 NuA4 histone acetyltransferase complex
Is a GO:0036411 H-NS-Cnu complex
Is a GO:0044545 NSL complex
Is a GO:0070419 nonhomologous end joining complex
Is a GO:0070461 SAGA-type complex
Is a GO:0070877 microprocessor complex
Is a GO:0070939 Dsl1/NZR complex
Is a GO:0097136 Bcl-2 family protein complex
Is a GO:1990354 activated SUMO-E1 ligase complex
Is a GO:0097149 centralspindlin complex
Is a GO:1990062 RPAP3/R2TP/prefoldin-like complex
Is a GO:1990221 L-cysteine desulfurase complex
Is a GO:1990696 USH2 complex
Is a GO:0097361 CIA complex
Is a GO:0036501 UFD1-NPL4 complex
Is a GO:1990745 EARP complex
Is a GO:1905543 interleukin-15 receptor complex
Is a GO:0036284 tubulobulbar complex
Is a GO:0097344 Rix1 complex
Is a GO:0099053 activating signal cointegrator 1 complex
Is a GO:0000417 HIR complex
Is a GO:0033186 CAF-1 complex
Is a GO:0035059 RCAF complex
Is a GO:0048189 Lid2 complex
Is a GO:0070209 ASTRA complex
Is a GO:0070603 SWI/SNF superfamily-type complex
Is a GO:0044777 single-stranded DNA-binding protein complex
Is a GO:0036375 Kibra-Ex-Mer complex
Is a GO:0044776 DNA polymerase III, core complex
Is a GO:0097179 protease inhibitor complex
Is a GO:0098046 type V protein secretion system complex
Is a GO:1990333 mitotic checkpoint complex, CDC20-MAD2 subcomplex
Is a GO:1990328 RNA polymerase II, RPB4-RPB7 subcomplex
Is a GO:0035808 meiotic recombination initiation complex
Is a GO:0035658 Mon1-Ccz1 complex
Is a GO:1990065 Dxr protein complex
Is a GO:1990463 lateral cortical node
Is a GO:1990728 mitotic spindle assembly checkpoint MAD1-MAD2 complex
Is a GO:1990713 survivin complex
Is a GO:0061576 acyl-CoA ceramide synthase complex
Is a GO:1990733 titin-telethonin complex
Is a GO:0097057 TRAF2-GSTP1 complex
Is a GO:0097058 CRLF-CLCF1 complex
Is a GO:0097059 CNTFR-CLCF1 complex
Is a GO:0030014 CCR4-NOT complex
Is a GO:1990125 DiaA complex
Is a GO:0038045 large latent transforming growth factor-beta complex
Is a GO:0036398 TCR signalosome
Is a GO:1990143 CoA-synthesizing protein complex
Is a GO:0072487 MSL complex
Is a GO:0097196 Shu complex
Is a GO:0098009 viral terminase, large subunit
Is a GO:0098745 Dcp1-Dcp2 complex
Is a GO:1990133 molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex
Is a GO:1990302 Bre1-Rad6 ubiquitin ligase complex
Is a GO:1990303 UBR1-RAD6 ubiquitin ligase complex
Is a GO:1990304 MUB1-RAD6-UBR2 ubiquitin ligase complex
Is a GO:1990305 RAD6-UBR2 ubiquitin ligase complex
Is a GO:1990306 RSP5-BUL ubiquitin ligase complex
Is a GO:0000439 core TFIIH complex
Is a GO:1990316 ATG1/ULK1 kinase complex
Is a GO:1990331 Hpa2 acetyltransferase complex
Is a GO:1990361 PKM2 pyruvate kinase complex
Is a GO:0061574 ASAP complex
Is a GO:1990200 SsuD-SsuE complex
Is a GO:0036454 growth factor complex
Is a GO:1990100 DnaB-DnaC complex
Is a GO:0036038 MKS complex
Is a GO:0061671 Cbp3p-Cbp6 complex
Is a GO:0044672 acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex
Is a GO:0044675 formyl-methanofuran dehydrogenase (tungsten enzyme) complex
Is a GO:0044676 formyl-methanofuran dehydrogenase (molybdenum enzyme) complex
Is a GO:0044677 methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex
Is a GO:1990112 RQC complex
Is a GO:0044697 HICS complex
Is a GO:1990563 extracellular exosome complex
Is a GO:0072669 tRNA-splicing ligase complex
Is a GO:0035693 NOS2-CD74 complex
Is a GO:0044609 DBIRD complex
Is a GO:1990788 GLI-SUFU complex
Is a GO:1990682 CSF1-CSF1R complex
Is a GO:0098820 trans-synaptic protein complex
Is a GO:0097347 TAM protein secretion complex
Is a GO:1990660 calprotectin complex
Is a GO:1990661 S100A8 complex
Is a GO:1990665 AnxA2-p11 complex
Is a GO:1990666 PCSK9-LDLR complex
Is a GO:1990667 PCSK9-AnxA2 complex
Is a GO:1990341 thrombospondin complex
Is a GO:1990393 3M complex
Is a GO:0036452 ESCRT complex
Is a GO:1990533 Dom34-Hbs1 complex
Is a GO:0097710 viral terminase, small subunit
Is a GO:1990957 NPHP complex
Is a GO:1990871 Vma12-Vma22 assembly complex
Is a GO:0099078 BORC complex
Is a GO:0031080 nuclear pore outer ring
Is a GO:0070762 nuclear pore transmembrane ring
Is a GO:0044611 nuclear pore inner ring
Is a GO:0044612 nuclear pore linkers
Is a GO:0044613 nuclear pore central transport channel
Is a GO:0044614 nuclear pore cytoplasmic filaments
Is a GO:0044615 nuclear pore nuclear basket
Is a GO:1990909 Wnt signalosome
Is a GO:1990811 Msd1-Wdr8-Pkl1 complex
Is a GO:0090665 glycoprotein complex
Is a GO:1990861 Ubp3-Bre5 deubiquitination complex
Is a GO:1905571 interleukin-10 receptor complex
Is a GO:1990964 actin cytoskeleton-regulatory complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Taxon
Date
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Product Form ID
Name
Synonym
Type
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0043234. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0043234 based on the entire annotation set Co-occurrence statistics for GO:0043234 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-05-19 Added SLIM goslim_chembl
2015-05-19 Deleted SLIM goslim_ChEMBL
2015-05-11 Added SLIM goslim_ChEMBL
2015-04-30 Deleted DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2015-04-30 Added DEFINITION A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2014-06-08 Deleted DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccaride) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2014-06-08 Added DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2014-05-18 Deleted DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
2014-05-18 Added DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccaride) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2010-02-14 Added DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
2010-02-14 Deleted DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
2009-02-25 Added XREF Wikipedia:Protein_complex
2008-06-16 Added SYNONYM protein-protein complex
2008-06-16 Added DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
2008-06-16 Deleted DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
2008-05-13 Added DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
2008-05-12 Deleted DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
2008-04-01 Updated RELATION is a GO:0032991 (macromolecular complex)
2004-10-30 Added TERM protein complex
2004-10-30 Added DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.

Term

Timestamp Action Category Detail
2004-10-30 Added TERM protein complex

Definition/synonyms

Timestamp Action Category Detail
2015-04-30 Deleted DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2015-04-30 Added DEFINITION A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2014-06-08 Deleted DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccaride) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2014-06-08 Added DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2014-05-18 Deleted DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
2014-05-18 Added DEFINITION Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccaride) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
2010-02-14 Added DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
2010-02-14 Deleted DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
2008-06-16 Added SYNONYM protein-protein complex
2008-06-16 Added DEFINITION Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
2008-06-16 Deleted DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
2008-05-13 Added DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
2008-05-12 Deleted DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
2004-10-30 Added DEFINITION Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0032991 (macromolecular complex)

Cross-references

Timestamp Action Category Detail
2009-02-25 Added XREF Wikipedia:Protein_complex

Other

Timestamp Action Category Detail
2015-05-19 Added SLIM goslim_chembl
2015-05-19 Deleted SLIM goslim_ChEMBL
2015-05-11 Added SLIM goslim_ChEMBL
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_generic
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_generic
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