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GO:0043190 ATP-binding cassette (ABC) transporter complex

A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.

Term Information

ID GO:0043190
Name ATP-binding cassette (ABC) transporter complex
Ontology Cellular Component
Definition A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
Comment

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir470

Synonyms

Type Synonym
related ATP-binding cassette (ABC) transporter activity
narrow ABC-type efflux permease activity
narrow ABC-type efflux porter activity
narrow mating pheromone exporter
narrow ABC-type uptake permease activity

Cross-references associated with this term:

Database ID
INTERPRO IPR005116
INTERPRO IPR008995
INTERPRO IPR013611

This term can be used instead of these obsolete terms:

GO:0042141 mating pheromone exporter (consider GO:0043190)
GO:0004009 ATP-binding cassette (ABC) transporter activity (consider GO:0043190)
GO:0015435 ABC-type efflux permease activity (consider GO:0043190)
GO:0015406 ABC-type uptake permease activity (consider GO:0043190)
GO:0015427 ABC-type efflux porter activity (consider GO:0043190)

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0005623 cell
GO:0032991 macromolecular complex
GO:0043234 protein complex
GO:0044464 cell part
GO:0016020 membrane
GO:0044425 membrane part
GO:0043190 ATP-binding cassette (ABC) transporter complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0055051 ATP-binding cassette (ABC) transporter complex, integrated substrate binding
I GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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