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GO:0004402 histone acetyltransferase activity

Term Information

ID GO:0004402
Name histone acetyltransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
Comment Note that the term 'histone lysine acetyltransferase activity ; GO:0046971' was merged into this term because only lysine residues are ever acetylated in histones, and so the term was redundant.
Secondary IDs GO:0004403 GO:0004404 GO:0004405 GO:0004406 GO:0043166 GO:0046971
GONUTS GO:0004402 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow H2A/H2B histone acetyltransferase activity
related nucleosome-histone acetyltransferase activity
narrow H3/H4 histone acetyltransferase activity
exact histone transacetylase activity
narrow H4/H2 histone acetyltransferase activity
narrow H4/H2A acetyltransferase activity
exact histone acetokinase activity
exact acetyl-CoA:histone acetyltransferase activity
exact histone lysine acetyltransferase activity
exact histone acetylase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.3.1.48
InterPro IPR000197
InterPro IPR008955
InterPro IPR009464
InterPro IPR013523
InterPro IPR014744
InterPro IPR016376
InterPro IPR017380
InterPro IPR019467
MetaCyc HISTONE-ACETYLTRANSFERASE-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004402:
Relationship To GO:0004402 Child Term Child Term Name
Regulates GO:0035034 histone acetyltransferase regulator activity
Is a GO:0010484 H3 histone acetyltransferase activity
Is a GO:0010485 H4 histone acetyltransferase activity
Is a GO:0043998 H2A histone acetyltransferase activity
Is a GO:0044013 H2B histone acetyltransferase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004402. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004402 based on the entire annotation set Co-occurrence statistics for GO:0004402 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-08-24 Added RELATION is a GO:0090595 (acetyl-CoA:L-lysine N6-acetyltransferase)
2014-08-24 Deleted RELATION is a GO:0008080 (N-acetyltransferase activity)
2011-12-08 Added RELATION is a GO:0008080 (N-acetyltransferase activity)
2011-12-08 Deleted RELATION is a GO:0004468 (lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)
2011-03-11 Added RELATION part of GO:0016573 (histone acetylation)
2009-11-15 Added SYNONYM nucleosome-histone acetyltransferase activity
2009-11-15 Deleted SYNONYM nucleosome-histone acetyltransferase activity
2009-11-15 Added SYNONYM H3/H4 histone acetyltransferase activity
2009-11-15 Added SYNONYM H2A/H2B histone acetyltransferase activity
2009-11-15 Added SYNONYM H4/H2 histone acetyltransferase activity
2009-11-15 Added SYNONYM H4/H2A acetyltransferase activity
2009-11-15 Added SECONDARY GO:0004406 (H3/H4 histone acetyltransferase activity)
2009-11-15 Added SECONDARY GO:0004405 (H2A/H2B histone acetyltransferase activity)
2009-11-15 Added SECONDARY GO:0043166 (H4/H2 histone acetyltransferase activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
2008-04-01 Updated RELATION is a GO:0004468 (lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)
2007-11-08 Added SYNONYM acetyl-CoA:histone acetyltransferase activity
2007-11-08 Added SYNONYM histone acetokinase activity
2007-11-08 Added SYNONYM histone transacetylase activity
2007-11-08 Added SYNONYM nucleosome-histone acetyltransferase activity
2007-08-09 Added SYNONYM histone acetylase activity
2007-08-09 Added SYNONYM histone lysine acetyltransferase activity
2007-08-09 Deleted SYNONYM histone acetylase activity
2007-08-09 Deleted SYNONYM histone lysine acetyltransferase activity
2004-10-31 Added SYNONYM histone acetylase activity
2004-06-15 Added SYNONYM histone lysine acetyltransferase activity
2004-06-15 Added SECONDARY GO:0046971 (histone lysine acetyltransferase activity)
2003-10-27 Added XREF MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN
2003-03-19 Updated TERM histone acetyltransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
2002-02-06 Updated TERM histone acetyltransferase
2001-04-03 Updated TERM histone acetyltransferase
2001-03-30 Added XREF EC:2.3.1.48
2001-03-30 Added TERM histone acetyltransferase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM histone acetyltransferase activity
2002-02-06 Updated TERM histone acetyltransferase
2001-04-03 Updated TERM histone acetyltransferase
2001-03-30 Added TERM histone acetyltransferase

Definition/synonyms

Timestamp Action Category Detail
2009-11-15 Added SYNONYM nucleosome-histone acetyltransferase activity
2009-11-15 Deleted SYNONYM nucleosome-histone acetyltransferase activity
2009-11-15 Added SYNONYM H3/H4 histone acetyltransferase activity
2009-11-15 Added SYNONYM H2A/H2B histone acetyltransferase activity
2009-11-15 Added SYNONYM H4/H2 histone acetyltransferase activity
2009-11-15 Added SYNONYM H4/H2A acetyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
2007-11-08 Added SYNONYM acetyl-CoA:histone acetyltransferase activity
2007-11-08 Added SYNONYM histone acetokinase activity
2007-11-08 Added SYNONYM histone transacetylase activity
2007-11-08 Added SYNONYM nucleosome-histone acetyltransferase activity
2007-08-09 Added SYNONYM histone acetylase activity
2007-08-09 Added SYNONYM histone lysine acetyltransferase activity
2007-08-09 Deleted SYNONYM histone acetylase activity
2007-08-09 Deleted SYNONYM histone lysine acetyltransferase activity
2004-10-31 Added SYNONYM histone acetylase activity
2004-06-15 Added SYNONYM histone lysine acetyltransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.

Relationships

Timestamp Action Category Detail
2014-08-24 Added RELATION is a GO:0090595 (acetyl-CoA:L-lysine N6-acetyltransferase)
2014-08-24 Deleted RELATION is a GO:0008080 (N-acetyltransferase activity)
2011-12-08 Added RELATION is a GO:0008080 (N-acetyltransferase activity)
2011-12-08 Deleted RELATION is a GO:0004468 (lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)
2011-03-11 Added RELATION part of GO:0016573 (histone acetylation)
2008-04-01 Updated RELATION is a GO:0004468 (lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN
2001-03-30 Added XREF EC:2.3.1.48

Other

Timestamp Action Category Detail
2009-11-15 Added SECONDARY GO:0004406 (H3/H4 histone acetyltransferase activity)
2009-11-15 Added SECONDARY GO:0004405 (H2A/H2B histone acetyltransferase activity)
2009-11-15 Added SECONDARY GO:0043166 (H4/H2 histone acetyltransferase activity)
2004-06-15 Added SECONDARY GO:0046971 (histone lysine acetyltransferase activity)
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