spacer

GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process

Term Information

ID GO:0043161
Name proteasome-mediated ubiquitin-dependent protein catabolic process
Ontology Biological Process
Definition The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
GONUTS GO:0043161 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact proteasomal ubiquitin-dependent protein catabolic process
exact proteasomal pathway
related proteasomal processing
related proteasome pathway
exact proteasomal ubiquitin-dependent protein degradation
exact proteasomal ubiquitin-dependent protein catabolism
exact proteasomal ubiquitin-dependent protein breakdown

Cross-references

Database ID
InterPro IPR015360

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043161:
Relationship To GO:0043161 Child Term Child Term Name
Is a GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation
Is a GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
Is a GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Regulates GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
Negatively regulates GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
Positively regulates GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Is a GO:0030433 ER-associated ubiquitin-dependent protein catabolic process
Is a GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
Is a GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process
Part of GO:1902376 protein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
Is a GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process
Is a GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway
Is a GO:0036369 transcription factor catabolic process
Is a GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0043161. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0043161 based on the entire annotation set Co-occurrence statistics for GO:0043161 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-10-31 Added SYNONYM proteasomal ubiquitin-dependent protein catabolic process
2013-10-31 Updated TERM proteasome-mediated ubiquitin-dependent protein catabolic process
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2008-04-01 Updated RELATION is a GO:0010498 (proteasomal protein catabolic process)
2008-04-01 Updated RELATION is a GO:0006511 (ubiquitin-dependent protein catabolic process)
2007-08-09 Added SYNONYM proteasomal pathway
2007-08-09 Added SYNONYM proteasomal processing
2007-08-09 Added SYNONYM proteasomal ubiquitin-dependent protein breakdown
2007-08-09 Added SYNONYM proteasomal ubiquitin-dependent protein catabolism
2007-08-09 Added SYNONYM proteasomal ubiquitin-dependent protein degradation
2007-08-09 Added SYNONYM proteasome pathway
2007-08-09 Deleted SYNONYM proteasomal ubiquitin-dependent protein catabolism
2007-08-09 Deleted SYNONYM proteasomal pathway
2007-08-09 Deleted SYNONYM proteasomal processing
2007-08-09 Deleted SYNONYM proteasomal ubiquitin-dependent protein breakdown
2007-08-09 Deleted SYNONYM proteasomal ubiquitin-dependent protein degradation
2007-08-09 Deleted SYNONYM proteasome pathway
2007-01-15 Updated TERM proteasomal ubiquitin-dependent protein catabolic process
2007-01-15 Added SYNONYM proteasomal ubiquitin-dependent protein catabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2005-12-04 Added SYNONYM proteasomal pathway
2005-08-10 Added SYNONYM proteasomal ubiquitin-dependent protein breakdown
2005-08-10 Added SYNONYM proteasomal ubiquitin-dependent protein degradation
2005-03-26 Added SYNONYM proteasomal processing
2005-03-26 Added SYNONYM proteasome pathway
2004-07-07 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2004-07-03 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteosome.
2004-06-27 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2004-05-12 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteosome.
2004-05-10 Added TERM proteasomal ubiquitin-dependent protein catabolism
2004-05-10 Added DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteosome.

Term

Timestamp Action Category Detail
2013-10-31 Updated TERM proteasome-mediated ubiquitin-dependent protein catabolic process
2007-01-15 Updated TERM proteasomal ubiquitin-dependent protein catabolic process
2004-05-10 Added TERM proteasomal ubiquitin-dependent protein catabolism

Definition/synonyms

Timestamp Action Category Detail
2013-10-31 Added SYNONYM proteasomal ubiquitin-dependent protein catabolic process
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2007-08-09 Added SYNONYM proteasomal pathway
2007-08-09 Added SYNONYM proteasomal processing
2007-08-09 Added SYNONYM proteasomal ubiquitin-dependent protein breakdown
2007-08-09 Added SYNONYM proteasomal ubiquitin-dependent protein catabolism
2007-08-09 Added SYNONYM proteasomal ubiquitin-dependent protein degradation
2007-08-09 Added SYNONYM proteasome pathway
2007-08-09 Deleted SYNONYM proteasomal ubiquitin-dependent protein catabolism
2007-08-09 Deleted SYNONYM proteasomal pathway
2007-08-09 Deleted SYNONYM proteasomal processing
2007-08-09 Deleted SYNONYM proteasomal ubiquitin-dependent protein breakdown
2007-08-09 Deleted SYNONYM proteasomal ubiquitin-dependent protein degradation
2007-08-09 Deleted SYNONYM proteasome pathway
2007-01-15 Added SYNONYM proteasomal ubiquitin-dependent protein catabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2005-12-04 Added SYNONYM proteasomal pathway
2005-08-10 Added SYNONYM proteasomal ubiquitin-dependent protein breakdown
2005-08-10 Added SYNONYM proteasomal ubiquitin-dependent protein degradation
2005-03-26 Added SYNONYM proteasomal processing
2005-03-26 Added SYNONYM proteasome pathway
2004-07-07 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2004-07-03 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteosome.
2004-06-27 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2004-05-12 Updated DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteosome.
2004-05-10 Added DEFINITION Destruction of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteosome.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0010498 (proteasomal protein catabolic process)
2008-04-01 Updated RELATION is a GO:0006511 (ubiquitin-dependent protein catabolic process)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
12ms