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GO:0043086 negative regulation of catalytic activity

Any process that stops or reduces the activity of an enzyme.

Term Information

ID GO:0043086
Name negative regulation of catalytic activity
Ontology Biological Process
Definition Any process that stops or reduces the activity of an enzyme.
Comment

Synonyms

Type Synonym
exact down-regulation of enzyme activity
exact downregulation of enzyme activity
narrow inhibition of enzyme activity
exact down regulation of enzyme activity
exact negative regulation of enzyme activity

Cross-references associated with this term:

Database ID
INTERPRO IPR014453
INTERPRO IPR010259

Web service: term information

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GTerm?id=termID&format=format

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0065007 biological regulation
GO:0065009 regulation of molecular function
GO:0050790 regulation of catalytic activity
GO:0044092 negative regulation of molecular function
GO:0043086 negative regulation of catalytic activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0051346 negative regulation of hydrolase activity
I GO:0051348 negative regulation of transferase activity
I GO:0051350 negative regulation of lyase activity
I GO:0051352 negative regulation of ligase activity
I GO:0051354 negative regulation of oxidoreductase activity
I GO:0048553 negative regulation of metalloenzyme activity
I GO:0031280 negative regulation of cyclase activity
I GO:0052199 negative regulation of catalytic activity in other organism during symbiotic interaction

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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