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GO:0042976 activation of Janus kinase activity

Term Information

ID GO:0042976
Name activation of Janus kinase activity
Ontology Biological Process
Definition The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
PMID:12479803
GONUTS GO:0042976 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact activation of JAK protein
related tyrosine phosphorylation of JAK protein
broad positive regulation of JAK protein activity by tyrosine phosphorylation
exact activation of JAK protein by tyrosine phosphorylation

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042976:
Relationship To GO:0042976 Child Term Child Term Name
Regulates GO:0010533 regulation of activation of Janus kinase activity
Positively regulates GO:0010536 positive regulation of activation of Janus kinase activity
Is a GO:0042977 activation of JAK2 kinase activity
Is a GO:0010531 activation of JAK1 kinase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0042976. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0042976 based on the entire annotation set Co-occurrence statistics for GO:0042976 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-05-18 Added RELATION part of GO:0046427 (positive regulation of JAK-STAT cascade)
2011-05-18 Deleted RELATION part of GO:0007259 (JAK-STAT cascade)
2009-02-25 Updated TERM activation of Janus kinase activity
2009-02-22 Updated TERM activation of Janus kinase activity
2008-05-13 Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-05-12 Deleted DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-04-07 Updated TERM activation of Janus kinase activity
2008-04-07 Added SYNONYM activation of JAK protein
2008-04-01 Updated RELATION is a GO:0018108 (peptidyl-tyrosine phosphorylation)
2008-04-01 Updated RELATION is a GO:0032147 (activation of protein kinase activity)
2008-04-01 Updated RELATION part of GO:0007259 (JAK-STAT cascade)
2008-02-11 Deleted SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2008-02-11 Deleted SYNONYM tyrosine phosphorylation of JAK protein
2008-02-11 Added SYNONYM activation of JAK protein by tyrosine phosphorylation
2008-02-11 Added SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2008-02-11 Added SYNONYM tyrosine phosphorylation of JAK protein
2008-02-11 Deleted SYNONYM activation of JAK protein by tyrosine phosphorylation
2007-10-25 Updated DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2007-09-10 Deleted SYNONYM activation of JAK protein
2007-08-09 Added SYNONYM tyrosine phosphorylation of JAK protein
2007-08-09 Added SYNONYM activation of JAK protein
2007-08-09 Added SYNONYM activation of JAK protein by tyrosine phosphorylation
2007-08-09 Added SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2007-08-09 Deleted SYNONYM activation of JAK protein
2007-08-09 Deleted SYNONYM activation of JAK protein by tyrosine phosphorylation
2007-08-09 Deleted SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2007-08-09 Deleted SYNONYM tyrosine phosphorylation of JAK protein
2004-08-01 Deleted SYNONYM positive regulation of of JAK protein activity by tyrosine phosphorylation
2004-08-01 Added SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2004-07-31 Updated TERM activation of JAK protein
2004-07-31 Added SYNONYM activation of JAK protein by tyrosine phosphorylation
2004-07-31 Added SYNONYM positive regulation of of JAK protein activity by tyrosine phosphorylation
2004-07-31 Added SYNONYM tyrosine phosphorylation of JAK protein
2004-04-19 Added SYNONYM activation of JAK protein
2004-04-16 Deleted SYNONYM activation of JAK protein
2003-10-10 Added SYNONYM activation of JAK protein
2003-10-10 Added DEFINITION The process of introducing a phosphoric group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2003-10-10 Added TERM tyrosine phosphorylation of JAK protein

Term

Timestamp Action Category Detail
2009-02-25 Updated TERM activation of Janus kinase activity
2009-02-22 Updated TERM activation of Janus kinase activity
2008-04-07 Updated TERM activation of Janus kinase activity
2004-07-31 Updated TERM activation of JAK protein
2003-10-10 Added TERM tyrosine phosphorylation of JAK protein

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-05-12 Deleted DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-04-07 Added SYNONYM activation of JAK protein
2008-02-11 Deleted SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2008-02-11 Deleted SYNONYM tyrosine phosphorylation of JAK protein
2008-02-11 Added SYNONYM activation of JAK protein by tyrosine phosphorylation
2008-02-11 Added SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2008-02-11 Added SYNONYM tyrosine phosphorylation of JAK protein
2008-02-11 Deleted SYNONYM activation of JAK protein by tyrosine phosphorylation
2007-10-25 Updated DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2007-09-10 Deleted SYNONYM activation of JAK protein
2007-08-09 Added SYNONYM tyrosine phosphorylation of JAK protein
2007-08-09 Added SYNONYM activation of JAK protein
2007-08-09 Added SYNONYM activation of JAK protein by tyrosine phosphorylation
2007-08-09 Added SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2007-08-09 Deleted SYNONYM activation of JAK protein
2007-08-09 Deleted SYNONYM activation of JAK protein by tyrosine phosphorylation
2007-08-09 Deleted SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2007-08-09 Deleted SYNONYM tyrosine phosphorylation of JAK protein
2004-08-01 Deleted SYNONYM positive regulation of of JAK protein activity by tyrosine phosphorylation
2004-08-01 Added SYNONYM positive regulation of JAK protein activity by tyrosine phosphorylation
2004-07-31 Added SYNONYM activation of JAK protein by tyrosine phosphorylation
2004-07-31 Added SYNONYM positive regulation of of JAK protein activity by tyrosine phosphorylation
2004-07-31 Added SYNONYM tyrosine phosphorylation of JAK protein
2004-04-19 Added SYNONYM activation of JAK protein
2004-04-16 Deleted SYNONYM activation of JAK protein
2003-10-10 Added SYNONYM activation of JAK protein
2003-10-10 Added DEFINITION The process of introducing a phosphoric group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.

Relationships

Timestamp Action Category Detail
2011-05-18 Added RELATION part of GO:0046427 (positive regulation of JAK-STAT cascade)
2011-05-18 Deleted RELATION part of GO:0007259 (JAK-STAT cascade)
2008-04-01 Updated RELATION is a GO:0018108 (peptidyl-tyrosine phosphorylation)
2008-04-01 Updated RELATION is a GO:0032147 (activation of protein kinase activity)
2008-04-01 Updated RELATION part of GO:0007259 (JAK-STAT cascade)
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