spacer
spacer
Type a query for QuickGO...
You can reach the search box using alt+9 (Win/IE), alt+shift+9 (Win/Firefox) or ctrl+9 (Mac)
EBIDatabasesQuickGO

GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis

A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the initiation of apoptosis (programmed cell death).

Term Information

ID GO:0042771
Name DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
Ontology Biological Process
Definition A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the initiation of apoptosis (programmed cell death).
Comment

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0016265 death
GO:0050896 response to stimulus
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0006950 response to stress
GO:0007154 cell communication
GO:0006974 response to DNA damage stimulus
GO:0008219 cell death
GO:0051716 cellular response to stimulus
GO:0048518 positive regulation of biological process
GO:0050794 regulation of cellular process
GO:0012501 programmed cell death
GO:0033554 cellular response to stress
GO:0006915 apoptosis
GO:0048522 positive regulation of cellular process
GO:0007165 signal transduction
GO:0010941 regulation of cell death
GO:0007242 intracellular signaling cascade
GO:0034984 cellular response to DNA damage stimulus
GO:0043067 regulation of programmed cell death
GO:0010942 positive regulation of cell death
GO:0042981 regulation of apoptosis
GO:0043068 positive regulation of programmed cell death
GO:0012502 induction of programmed cell death
GO:0042770 DNA damage response, signal transduction
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0043065 positive regulation of apoptosis
GO:0006917 induction of apoptosis
GO:0008629 induction of apoptosis by intracellular signals
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
spacer
14ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-23-04-03-36
Terminal
spacer