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GO:0042729 DASH complex

Term Information

ID GO:0042729
Name DASH complex
Ontology Cellular Component
Definition A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
PMID:11782438 PMID:11799062 PMID:15632076 PMID:15640796
Comment Note that this complex is conserved in fungi but has not been observed in metazoans.
Secondary IDs GO:0043925 GO:0043926
GONUTS GO:0042729 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact condensed nuclear chromosome kinetochore-associated DASH complex
exact DDD complex
exact Dam1 complex
exact Duo1p-Dam1p-Dad1p complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Protein complexes

Database ID Name
IntAct dash_yeast DASH complex

Cross-references

Database ID
InterPro IPR013251
InterPro IPR013958
InterPro IPR013959
InterPro IPR013960
InterPro IPR013962
InterPro IPR013963
InterPro IPR013964
InterPro IPR013965
InterPro IPR013966

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042729:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
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Date
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Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0042729. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0042729 based on the entire annotation set Co-occurrence statistics for GO:0042729 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-10-29 Deleted RELATION is a GO:0043234 (protein complex)
2012-06-23 Added RELATION is a GO:0000942 (condensed nuclear chromosome outer kinetochore)
2012-06-23 Deleted RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2012-06-23 Deleted RELATION is a GO:0044454 (nuclear chromosome part)
2009-03-14 Deleted RELATION is a GO:0044428 (nuclear part)
2009-02-28 Added RELATION is a GO:0044454 (nuclear chromosome part)
2009-02-28 Added RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2009-02-28 Added SECONDARY GO:0043926 (kinetochore-associated DASH complex)
2009-02-28 Added SECONDARY GO:0043925 (microtubule-associated DASH complex)
2009-02-28 Added SYNONYM condensed nuclear chromosome kinetochore-associated DASH complex
2009-02-28 Deleted DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complexes associate with kinetochores or microtubules and play a role spindle attachment, chromosome segregation and spindle stability.
2009-02-28 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
2008-10-02 Added RELATION is a GO:0044428 (nuclear part)
2008-07-12 Deleted DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2008-07-12 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complexes associate with kinetochores or microtubules and play a role spindle attachment, chromosome segregation and spindle stability.
2008-07-12 Added RELATION is a GO:0043234 (protein complex)
2008-07-12 Deleted RELATION is a GO:0044454 (nuclear chromosome part)
2008-07-12 Deleted RELATION is a GO:0005875 (microtubule associated complex)
2008-07-12 Deleted RELATION part of GO:0005828 (kinetochore microtubule)
2008-07-12 Deleted RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2008-05-13 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2008-05-12 Deleted DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2008-04-01 Updated RELATION is a GO:0044454 (nuclear chromosome part)
2008-04-01 Updated RELATION part of GO:0005828 (kinetochore microtubule)
2008-04-01 Updated RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2008-04-01 Updated RELATION is a GO:0005875 (microtubule associated complex)
2007-08-09 Added SYNONYM DDD complex
2007-08-09 Added SYNONYM Dam1 complex
2007-08-09 Added SYNONYM Duo1p-Dam1p-Dad1p complex
2007-08-09 Deleted SYNONYM DDD complex
2007-08-09 Deleted SYNONYM Dam1 complex
2007-08-09 Deleted SYNONYM Duo1p-Dam1p-Dad1p complex
2007-05-27 Updated DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2005-05-09 Added SYNONYM Dam1 complex
2004-04-19 Added SYNONYM DDD complex
2004-04-19 Added SYNONYM Duo1p-Dam1p-Dad1p complex
2004-04-16 Deleted SYNONYM DDD complex
2004-04-16 Deleted SYNONYM Duo1p-Dam1p-Dad1p complex
2004-03-18 Updated DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role chromosome segregation and spindle stability.
2003-07-08 Updated DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1. Associating with microtubules and kinetochores, the complex plays a role chromosome segregation and spindle stability.
2003-05-10 Added SYNONYM Duo1p-Dam1p-Dad1p complex
2003-05-10 Added SYNONYM DDD complex
2003-05-10 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1. Associating with microtubules and kineochores, the complex plays a role chromosome segregation and spindle stability.
2003-05-10 Added TERM DASH complex

Term

Timestamp Action Category Detail
2003-05-10 Added TERM DASH complex

Definition/synonyms

Timestamp Action Category Detail
2009-02-28 Added SYNONYM condensed nuclear chromosome kinetochore-associated DASH complex
2009-02-28 Deleted DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complexes associate with kinetochores or microtubules and play a role spindle attachment, chromosome segregation and spindle stability.
2009-02-28 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
2008-07-12 Deleted DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2008-07-12 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complexes associate with kinetochores or microtubules and play a role spindle attachment, chromosome segregation and spindle stability.
2008-05-13 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2008-05-12 Deleted DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2007-08-09 Added SYNONYM DDD complex
2007-08-09 Added SYNONYM Dam1 complex
2007-08-09 Added SYNONYM Duo1p-Dam1p-Dad1p complex
2007-08-09 Deleted SYNONYM DDD complex
2007-08-09 Deleted SYNONYM Dam1 complex
2007-08-09 Deleted SYNONYM Duo1p-Dam1p-Dad1p complex
2007-05-27 Updated DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role spindle attachment, chromosome segregation and spindle stability.
2005-05-09 Added SYNONYM Dam1 complex
2004-04-19 Added SYNONYM DDD complex
2004-04-19 Added SYNONYM Duo1p-Dam1p-Dad1p complex
2004-04-16 Deleted SYNONYM DDD complex
2004-04-16 Deleted SYNONYM Duo1p-Dam1p-Dad1p complex
2004-03-18 Updated DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. Associating with microtubules and kinetochores, the complex plays a role chromosome segregation and spindle stability.
2003-07-08 Updated DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1. Associating with microtubules and kinetochores, the complex plays a role chromosome segregation and spindle stability.
2003-05-10 Added SYNONYM Duo1p-Dam1p-Dad1p complex
2003-05-10 Added SYNONYM DDD complex
2003-05-10 Added DEFINITION A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1. Associating with microtubules and kineochores, the complex plays a role chromosome segregation and spindle stability.

Relationships

Timestamp Action Category Detail
2012-10-29 Deleted RELATION is a GO:0043234 (protein complex)
2012-06-23 Added RELATION is a GO:0000942 (condensed nuclear chromosome outer kinetochore)
2012-06-23 Deleted RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2012-06-23 Deleted RELATION is a GO:0044454 (nuclear chromosome part)
2009-03-14 Deleted RELATION is a GO:0044428 (nuclear part)
2009-02-28 Added RELATION is a GO:0044454 (nuclear chromosome part)
2009-02-28 Added RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2008-10-02 Added RELATION is a GO:0044428 (nuclear part)
2008-07-12 Added RELATION is a GO:0043234 (protein complex)
2008-07-12 Deleted RELATION is a GO:0044454 (nuclear chromosome part)
2008-07-12 Deleted RELATION is a GO:0005875 (microtubule associated complex)
2008-07-12 Deleted RELATION part of GO:0005828 (kinetochore microtubule)
2008-07-12 Deleted RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2008-04-01 Updated RELATION is a GO:0044454 (nuclear chromosome part)
2008-04-01 Updated RELATION part of GO:0005828 (kinetochore microtubule)
2008-04-01 Updated RELATION part of GO:0000778 (condensed nuclear chromosome kinetochore)
2008-04-01 Updated RELATION is a GO:0005875 (microtubule associated complex)

Other

Timestamp Action Category Detail
2009-02-28 Added SECONDARY GO:0043926 (kinetochore-associated DASH complex)
2009-02-28 Added SECONDARY GO:0043925 (microtubule-associated DASH complex)
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