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GO:0042729 DASH complex

A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.

Term Information

ID GO:0042729
Name DASH complex
Ontology Cellular Component
Definition A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
Comment Note that this complex is conserved in fungi but has not been observed in metazoans.

Synonyms

Type Synonym
exact condensed nuclear chromosome kinetochore-associated DASH complex
exact Duo1p-Dam1p-Dad1p complex
exact DDD complex
exact Dam1 complex

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Ancestor Chart

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0005575 cellular_component
GO:0005623 cell
GO:0032991 macromolecular complex
GO:0043226 organelle
GO:0043228 non-membrane-bounded organelle
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0043234 protein complex
GO:0044422 organelle part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0044446 intracellular organelle part
GO:0043232 intracellular non-membrane-bounded organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0005634 nucleus
GO:0005694 chromosome
GO:0000793 condensed chromosome
GO:0044427 chromosomal part
GO:0044428 nuclear part
GO:0000775 chromosome, centromeric region
GO:0000779 condensed chromosome, centromeric region
GO:0000228 nuclear chromosome
GO:0000776 kinetochore
GO:0000794 condensed nuclear chromosome
GO:0044454 nuclear chromosome part
GO:0000777 condensed chromosome kinetochore
GO:0000780 condensed nuclear chromosome, centromeric region
GO:0000778 condensed nuclear chromosome kinetochore
GO:0042729 DASH complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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