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GO:0042612 MHC class I protein complex

Term Information

ID GO:0042612
Name MHC class I protein complex
Ontology Cellular Component
Definition A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
Comment See also the cellular component term 'MHC class I peptide loading complex ; GO:0042824'.
GONUTS GO:0042612 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR010579
InterPro IPR015707
InterPro IPR027648
UniProtKB-KW MHC I

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0003820 class I major histocompatibility complex antigen CONSIDER GO:0042612
GO:0030106 MHC class I receptor activity CONSIDER GO:0042612

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042612:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0042612. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0042612 based on the entire annotation set Co-occurrence statistics for GO:0042612 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
2008-05-12 Deleted DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
2008-04-01 Updated RELATION is a GO:0042611 (MHC protein complex)
2006-11-21 Updated DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
2003-03-26 Added DEFINITION A transmembrane protein complex usually composed of a polymorphic alpha chain and an invariant beta2-microglobin chain. Functions in the presentation of endogenous antigen to the immune system.
2003-03-19 Added TERM MHC class I protein complex

Term

Timestamp Action Category Detail
2003-03-19 Added TERM MHC class I protein complex

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
2008-05-12 Deleted DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
2006-11-21 Updated DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
2003-03-26 Added DEFINITION A transmembrane protein complex usually composed of a polymorphic alpha chain and an invariant beta2-microglobin chain. Functions in the presentation of endogenous antigen to the immune system.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0042611 (MHC protein complex)
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