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GO:0042552 myelination

Term Information

ID GO:0042552
Name myelination
Ontology Biological Process
Definition The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
GONUTS GO:0042552 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related myelinogenesis

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0032501 multicellular organismal process never_in_taxon 4896 Schizosaccharomyces pombe
GO:0032501 multicellular organismal process never_in_taxon 4932 Saccharomyces cerevisiae
GO:0032501 multicellular organismal process only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR026965
InterPro IPR029555
InterPro IPR031284
InterPro IPR032658
Wikipedia Myelin

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042552:
Relationship To GO:0042552 Child Term Child Term Name
Regulates GO:0031641 regulation of myelination
Negatively regulates GO:0031642 negative regulation of myelination
Positively regulates GO:0031643 positive regulation of myelination
Part of GO:0032288 myelin assembly
Is a GO:0048897 myelination of lateral line nerve axons
Is a GO:0022010 central nervous system myelination
Is a GO:0022011 myelination in peripheral nervous system
Part of GO:0043217 myelin maintenance

Protein Annotation

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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0042552. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0042552 based on the entire annotation set Co-occurrence statistics for GO:0042552 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-12-13 Added SYNONYM myelinogenesis
2010-12-03 Added DEFINITION The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-03 Deleted DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2009-03-29 Added XREF Wikipedia:Myelin
2008-05-13 Added DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2008-05-12 Deleted DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2008-04-01 Updated RELATION is a GO:0008366 (axon ensheathment)
2006-09-28 Deleted SYNONYM myelin formation
2006-09-26 Updated DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2004-09-11 Added SYNONYM myelin formation
2004-09-10 Updated DEFINITION The process by which oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2002-11-27 Added DEFINITION The process by which myelin is laid down as an insulating layer around the axons of certain nerve cells.
2002-10-31 Added TERM myelination

Term

Timestamp Action Category Detail
2002-10-31 Added TERM myelination

Definition/synonyms

Timestamp Action Category Detail
2014-12-13 Added SYNONYM myelinogenesis
2010-12-03 Added DEFINITION The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-03 Deleted DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2008-05-13 Added DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2008-05-12 Deleted DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2006-09-28 Deleted SYNONYM myelin formation
2006-09-26 Updated DEFINITION The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2004-09-11 Added SYNONYM myelin formation
2004-09-10 Updated DEFINITION The process by which oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2002-11-27 Added DEFINITION The process by which myelin is laid down as an insulating layer around the axons of certain nerve cells.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008366 (axon ensheathment)

Cross-references

Timestamp Action Category Detail
2009-03-29 Added XREF Wikipedia:Myelin
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