spacer

GO:0042393 histone binding

Term Information

ID GO:0042393
Name histone binding
Ontology Molecular Function
Definition Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
GONUTS GO:0042393 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related histone-specific chaperone activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Binding term considerationsLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_generic149
goslim_yeast169

Cross-Ontology Relations

Relation Other Ontology ID Term
has_input CHEBI CHEBI:15358 histone

Cross-references

Database ID
InterPro IPR003105
InterPro IPR013523
InterPro IPR018465
InterPro IPR020693
InterPro IPR021998
InterPro IPR029289
InterPro IPR029295

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0003762 histone-specific chaperone activity CONSIDER GO:0042393

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042393:
Relationship To GO:0042393 Child Term Child Term Name
Is a GO:0035064 methylated histone binding
Is a GO:0031493 nucleosomal histone binding
Is a GO:0070577 lysine-acetylated histone binding

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0042393. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0042393 based on the entire annotation set Co-occurrence statistics for GO:0042393 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_generic
2012-02-10 Added SLIM goslim_generic
2011-08-14 Added SLIM goslim_yeast
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2009-07-03 Deleted DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2008-05-13 Added DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2008-05-12 Deleted DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
2007-08-09 Added SYNONYM histone-specific chaperone activity
2007-08-09 Deleted SYNONYM histone-specific chaperone activity
2005-08-10 Added SYNONYM histone-specific chaperone activity
2003-06-10 Updated TERM histone binding
2003-03-26 Updated DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2003-03-19 Updated TERM histone binding activity
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2002-07-24 Added TERM histone binding

Term

Timestamp Action Category Detail
2003-06-10 Updated TERM histone binding
2003-03-19 Updated TERM histone binding activity
2002-07-24 Added TERM histone binding

Definition/synonyms

Timestamp Action Category Detail
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2009-07-03 Deleted DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2008-05-13 Added DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2008-05-12 Deleted DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2007-08-09 Added SYNONYM histone-specific chaperone activity
2007-08-09 Deleted SYNONYM histone-specific chaperone activity
2005-08-10 Added SYNONYM histone-specific chaperone activity
2003-03-26 Updated DEFINITION Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_generic
2012-02-10 Added SLIM goslim_generic
2011-08-14 Added SLIM goslim_yeast
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
12ms