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GO:0042177 negative regulation of protein catabolic process

Term Information

ID GO:0042177
Name negative regulation of protein catabolic process
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
PMID:10207076
GONUTS GO:0042177 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact down regulation of protein catabolic process
exact down-regulation of protein catabolic process
exact downregulation of protein catabolic process
narrow inhibition of protein catabolic process
exact negative regulation of protein breakdown
exact negative regulation of protein catabolism
exact negative regulation of protein degradation

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042177:
Relationship To GO:0042177 Child Term Child Term Name
Is a GO:0060311 negative regulation of elastin catabolic process
Is a GO:0051045 negative regulation of membrane protein ectodomain proteolysis
Is a GO:0002629 negative regulation of proteolysis associated with antigen processing and presentation
Is a GO:1903363 negative regulation of cellular protein catabolic process
Is a GO:1901799 negative regulation of proteasomal protein catabolic process

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0042177. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0042177 based on the entire annotation set Co-occurrence statistics for GO:0042177 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2008-04-01 Updated RELATION is a GO:0009895 (negative regulation of catabolic process)
2008-04-01 Updated RELATION is a GO:0042176 (regulation of protein catabolic process)
2008-04-01 Added RELATION negatively regulates GO:0030163 (protein catabolic process)
2008-04-01 Updated RELATION is a GO:0051248 (negative regulation of protein metabolic process)
2007-08-09 Added SYNONYM down regulation of protein catabolic process
2007-08-09 Added SYNONYM down-regulation of protein catabolic process
2007-08-09 Added SYNONYM downregulation of protein catabolic process
2007-08-09 Added SYNONYM inhibition of protein catabolic process
2007-08-09 Added SYNONYM negative regulation of protein breakdown
2007-08-09 Added SYNONYM negative regulation of protein catabolism
2007-08-09 Added SYNONYM negative regulation of protein degradation
2007-08-09 Deleted SYNONYM down regulation of protein catabolic process
2007-08-09 Deleted SYNONYM down-regulation of protein catabolic process
2007-08-09 Deleted SYNONYM downregulation of protein catabolic process
2007-08-09 Deleted SYNONYM inhibition of protein catabolic process
2007-08-09 Deleted SYNONYM negative regulation of protein catabolism
2007-08-09 Deleted SYNONYM negative regulation of protein breakdown
2007-08-09 Deleted SYNONYM negative regulation of protein degradation
2007-02-23 Added SYNONYM down regulation of protein catabolic process
2007-02-23 Added SYNONYM down-regulation of protein catabolic process
2007-02-23 Added SYNONYM downregulation of protein catabolic process
2007-02-23 Added SYNONYM inhibition of protein catabolic process
2007-01-15 Updated TERM negative regulation of protein catabolic process
2007-01-15 Added SYNONYM negative regulation of protein catabolism
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2005-08-10 Added SYNONYM negative regulation of protein breakdown
2005-08-10 Added SYNONYM negative regulation of protein degradation
2003-04-02 Updated DEFINITION Any process that stops, prevents or reduces the rate of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. Prohibitins comprise a protein family in eukaryotic cells with potential roles in senescence and tumor suppression. Prohibitins regulate the turnover of membrane proteins by the m-AAA protease, a conserved ATP-dependent protease in the inner membrane of mitochondria.
2002-08-15 Updated TERM negative regulation of protein catabolism
2002-07-15 Updated TERM negative regulation of protein degradation
2002-03-22 Added TERM inhibition of protein degradation

Term

Timestamp Action Category Detail
2007-01-15 Updated TERM negative regulation of protein catabolic process
2002-08-15 Updated TERM negative regulation of protein catabolism
2002-07-15 Updated TERM negative regulation of protein degradation
2002-03-22 Added TERM inhibition of protein degradation

Definition/synonyms

Timestamp Action Category Detail
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2007-08-09 Added SYNONYM down regulation of protein catabolic process
2007-08-09 Added SYNONYM down-regulation of protein catabolic process
2007-08-09 Added SYNONYM downregulation of protein catabolic process
2007-08-09 Added SYNONYM inhibition of protein catabolic process
2007-08-09 Added SYNONYM negative regulation of protein breakdown
2007-08-09 Added SYNONYM negative regulation of protein catabolism
2007-08-09 Added SYNONYM negative regulation of protein degradation
2007-08-09 Deleted SYNONYM down regulation of protein catabolic process
2007-08-09 Deleted SYNONYM down-regulation of protein catabolic process
2007-08-09 Deleted SYNONYM downregulation of protein catabolic process
2007-08-09 Deleted SYNONYM inhibition of protein catabolic process
2007-08-09 Deleted SYNONYM negative regulation of protein catabolism
2007-08-09 Deleted SYNONYM negative regulation of protein breakdown
2007-08-09 Deleted SYNONYM negative regulation of protein degradation
2007-02-23 Added SYNONYM down regulation of protein catabolic process
2007-02-23 Added SYNONYM down-regulation of protein catabolic process
2007-02-23 Added SYNONYM downregulation of protein catabolic process
2007-02-23 Added SYNONYM inhibition of protein catabolic process
2007-01-15 Added SYNONYM negative regulation of protein catabolism
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2005-08-10 Added SYNONYM negative regulation of protein breakdown
2005-08-10 Added SYNONYM negative regulation of protein degradation
2003-04-02 Updated DEFINITION Any process that stops, prevents or reduces the rate of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. Prohibitins comprise a protein family in eukaryotic cells with potential roles in senescence and tumor suppression. Prohibitins regulate the turnover of membrane proteins by the m-AAA protease, a conserved ATP-dependent protease in the inner membrane of mitochondria.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0009895 (negative regulation of catabolic process)
2008-04-01 Updated RELATION is a GO:0042176 (regulation of protein catabolic process)
2008-04-01 Added RELATION negatively regulates GO:0030163 (protein catabolic process)
2008-04-01 Updated RELATION is a GO:0051248 (negative regulation of protein metabolic process)
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