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GO:0042116 macrophage activation

Term Information

ID GO:0042116
Name macrophage activation
Ontology Biological Process
Definition A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
PMID:14506301
GONUTS GO:0042116 Wiki Page

Cross-Ontology Relations

Relation Other Ontology ID Term
has_input CL CL:0000235 macrophage

Cross-references

Database ID
InterPro IPR027168
InterPro IPR027190

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042116:
Relationship To GO:0042116 Child Term Child Term Name
Is a GO:0001774 microglial cell activation
Is a GO:0002281 macrophage activation involved in immune response
Regulates GO:0043030 regulation of macrophage activation
Negatively regulates GO:0043031 negative regulation of macrophage activation
Positively regulates GO:0043032 positive regulation of macrophage activation

Protein Annotation

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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0042116. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0042116 based on the entire annotation set Co-occurrence statistics for GO:0042116 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2008-05-12 Deleted DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2008-04-01 Updated RELATION is a GO:0002274 (myeloid leukocyte activation)
2006-09-19 Updated DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2003-11-11 Updated DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-04 Added DEFINITION A change in morphology and behavior of a macrophage, a phagocytic cell of mammalian tissues, resulting from exposure to a mitogen or to an antigen to which it had been primed.
2002-02-21 Added TERM macrophage activation

Term

Timestamp Action Category Detail
2002-02-21 Added TERM macrophage activation

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2008-05-12 Deleted DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2006-09-19 Updated DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2003-11-11 Updated DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-04 Added DEFINITION A change in morphology and behavior of a macrophage, a phagocytic cell of mammalian tissues, resulting from exposure to a mitogen or to an antigen to which it had been primed.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0002274 (myeloid leukocyte activation)
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