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GO:0038179 neurotrophin signaling pathway

Term Information

ID GO:0038179
Name neurotrophin signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.
PMID:17466268
Comment There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors.
GONUTS GO:0038179 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact neurotrophin receptor signaling pathway

GO Discussions

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If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0001010 GO:0070848 response to growth factor never_in_taxon 2, 2157, 4751 Fungi or Bacteria or Archaea
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0038179:
Relationship To GO:0038179 Child Term Child Term Name
Is a GO:0038180 nerve growth factor signaling pathway
Part of GO:0005030 neurotrophin receptor activity
Is a GO:0048011 neurotrophin TRK receptor signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0038179. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0038179 based on the entire annotation set Co-occurrence statistics for GO:0038179 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-03-29 Added DEFINITION A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.
2013-03-29 Added SYNONYM neurotrophin receptor signaling pathway
2013-03-29 Added RELATION is a GO:0071363 (cellular response to growth factor stimulus)
2013-03-29 Added RELATION is a GO:0007166 (cell surface receptor signaling pathway)
2013-03-29 Added TERM neurotrophin signaling pathway

Term

Timestamp Action Category Detail
2013-03-29 Added TERM neurotrophin signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2013-03-29 Added DEFINITION A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.
2013-03-29 Added SYNONYM neurotrophin receptor signaling pathway

Relationships

Timestamp Action Category Detail
2013-03-29 Added RELATION is a GO:0071363 (cellular response to growth factor stimulus)
2013-03-29 Added RELATION is a GO:0007166 (cell surface receptor signaling pathway)
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