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GO:0038011 negative regulation of signal transduction by receptor internalization

Term Information

ID GO:0038011
Name negative regulation of signal transduction by receptor internalization
Ontology Biological Process
Definition Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.
PMID:17908284 PMID:19696798
GONUTS GO:0038011 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative regulation of signaling pathway by receptor endocytosis

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
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Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0038011:
Relationship To GO:0038011 Child Term Child Term Name
Is a GO:0038012 negative regulation of Wnt signaling pathway by Wnt receptor internalization
Is a GO:0038014 negative regulation of insulin receptor signaling pathway by insulin receptor internalization

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0038011. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0038011 based on the entire annotation set Co-occurrence statistics for GO:0038011 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-10-31 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2012-10-29 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2011-06-26 Added RELATION is a GO:0038009 (regulation of signal transduction by receptor internalization)
2011-06-26 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2011-06-26 Added SYNONYM negative regulation of signaling pathway by receptor endocytosis
2011-06-26 Added DEFINITION Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.
2011-06-26 Added TERM negative regulation of signal transduction by receptor internalization

Term

Timestamp Action Category Detail
2011-06-26 Added TERM negative regulation of signal transduction by receptor internalization

Definition/synonyms

Timestamp Action Category Detail
2011-06-26 Added SYNONYM negative regulation of signaling pathway by receptor endocytosis
2011-06-26 Added DEFINITION Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.

Relationships

Timestamp Action Category Detail
2012-10-31 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2012-10-29 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2011-06-26 Added RELATION is a GO:0038009 (regulation of signal transduction by receptor internalization)
2011-06-26 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
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