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GO:0036398 TCR signalosome

Term Information

ID GO:0036398
Name TCR signalosome
Ontology Cellular Component
Definition A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.
PMID:17534068 PMID:20107804 PMID:22426112
GONUTS GO:0036398 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact linker for activation of T cells signalosome
exact LAT signalosome

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0036398:
Relationship To GO:0036398 Child Term Child Term Name
Has part GO:0042101 T cell receptor complex

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0036398. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0036398 based on the entire annotation set Co-occurrence statistics for GO:0036398 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-07-22 Added TERM TCR signalosome
2013-07-22 Added SYNONYM LAT signalosome
2013-07-22 Added SYNONYM linker for activation of T cells signalosome
2013-07-22 Added DEFINITION A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.
2013-07-22 Added RELATION is a GO:0043234 (protein complex)

Term

Timestamp Action Category Detail
2013-07-22 Added TERM TCR signalosome

Definition/synonyms

Timestamp Action Category Detail
2013-07-22 Added SYNONYM LAT signalosome
2013-07-22 Added SYNONYM linker for activation of T cells signalosome
2013-07-22 Added DEFINITION A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.

Relationships

Timestamp Action Category Detail
2013-07-22 Added RELATION is a GO:0043234 (protein complex)
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