spacer

GO:0035422 activation of MAPKKK activity involved in innate immune response

Term Information

ID GO:0035422
Name activation of MAPKKK activity involved in innate immune response
Ontology Biological Process
Definition Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
GONUTS GO:0035422 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000016 GO:0000185 activation of MAPKKK activity only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0035422:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0035422. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0035422 based on the entire annotation set Co-occurrence statistics for GO:0035422 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-01-29 Added RELATION positively regulates GO:0038077 (MAP kinase kinase kinase activity involved in innate immune response)
2012-01-29 Deleted RELATION part of GO:0035420 (MAPK cascade involved in innate immune response)
2010-10-11 Deleted RELATION is a GO:0002252 (immune effector process)
2010-09-26 Added RELATION is a GO:0002252 (immune effector process)
2010-03-31 Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
2010-03-31 Added TERM activation of MAPKKK activity involved in innate immune response
2010-03-31 Added RELATION part of GO:0035420 (MAPK cascade involved in innate immune response)
2010-03-31 Added RELATION is a GO:0002758 (innate immune response-activating signal transduction)
2010-03-31 Added RELATION is a GO:0000185 (activation of MAPKKK activity)

Term

Timestamp Action Category Detail
2010-03-31 Added TERM activation of MAPKKK activity involved in innate immune response

Definition/synonyms

Timestamp Action Category Detail
2010-03-31 Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.

Relationships

Timestamp Action Category Detail
2012-01-29 Added RELATION positively regulates GO:0038077 (MAP kinase kinase kinase activity involved in innate immune response)
2012-01-29 Deleted RELATION part of GO:0035420 (MAPK cascade involved in innate immune response)
2010-10-11 Deleted RELATION is a GO:0002252 (immune effector process)
2010-09-26 Added RELATION is a GO:0002252 (immune effector process)
2010-03-31 Added RELATION part of GO:0035420 (MAPK cascade involved in innate immune response)
2010-03-31 Added RELATION is a GO:0002758 (innate immune response-activating signal transduction)
2010-03-31 Added RELATION is a GO:0000185 (activation of MAPKKK activity)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
14ms