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GO:0035329 hippo signaling

Term Information

ID GO:0035329
Name hippo signaling
Ontology Biological Process
Definition The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
PMID:17318211 PMID:18328423
GONUTS GO:0035329 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow Salvador-Warts-Hippo signaling pathway
exact hippo signaling pathway
related hippo signaling cascade
exact hippo signal transduction
narrow SWH pathway
related hippo signalling cascade

GO Discussions

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Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR016361
InterPro IPR027253
InterPro IPR028741
InterPro IPR028742
InterPro IPR030030

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0035329:
Relationship To GO:0035329 Child Term Child Term Name
Regulates GO:0035330 regulation of hippo signaling
Negatively regulates GO:0035331 negative regulation of hippo signaling
Positively regulates GO:0035332 positive regulation of hippo signaling

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0035329. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0035329 based on the entire annotation set Co-occurrence statistics for GO:0035329 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-14 Added SYNONYM hippo signal transduction
2013-12-04 Updated TERM hippo signaling
2013-12-04 Added SYNONYM hippo signaling cascade
2013-12-04 Added SYNONYM hippo signalling cascade
2013-12-04 Deleted SYNONYM hippo signalling cascade
2010-11-17 Added SYNONYM hippo signalling cascade
2010-07-25 Updated TERM hippo signaling cascade
2010-07-25 Added SYNONYM hippo signaling pathway
2010-06-04 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-05-16 Added RELATION is a GO:0035556 (intracellular signal transduction)
2010-02-28 Added SYNONYM Salvador-Warts-Hippo signaling pathway
2010-02-28 Added SYNONYM SWH pathway
2010-02-28 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-28 Added TERM hippo signaling pathway
2010-02-28 Added DEFINITION The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.

Term

Timestamp Action Category Detail
2013-12-04 Updated TERM hippo signaling
2010-07-25 Updated TERM hippo signaling cascade
2010-02-28 Added TERM hippo signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2013-12-14 Added SYNONYM hippo signal transduction
2013-12-04 Added SYNONYM hippo signaling cascade
2013-12-04 Added SYNONYM hippo signalling cascade
2013-12-04 Deleted SYNONYM hippo signalling cascade
2010-11-17 Added SYNONYM hippo signalling cascade
2010-07-25 Added SYNONYM hippo signaling pathway
2010-02-28 Added SYNONYM Salvador-Warts-Hippo signaling pathway
2010-02-28 Added SYNONYM SWH pathway
2010-02-28 Added DEFINITION The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.

Relationships

Timestamp Action Category Detail
2010-06-04 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-05-16 Added RELATION is a GO:0035556 (intracellular signal transduction)
2010-02-28 Added RELATION is a GO:0023034 (intracellular signaling pathway)
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