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GO:0035278 negative regulation of translation involved in gene silencing by miRNA

Term Information

ID GO:0035278
Name negative regulation of translation involved in gene silencing by miRNA
Ontology Biological Process
Definition The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
PMID:14744438 PMID:15196554
GONUTS GO:0035278 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related miRNA-mediated gene silencing, negative regulation of translation
exact gene silencing by miRNA, negative regulation of translation
exact down regulation of translation involved in gene silencing by miRNA
exact downregulation of translation involved in gene silencing by miRNA
narrow inhibition of translation involved in gene silencing by miRNA
exact down-regulation of translation involved in gene silencing by miRNA
exact negative regulation of translation involved in gene silencing by microRNA

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0035278:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0035278. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0035278 based on the entire annotation set Co-occurrence statistics for GO:0035278 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-06-26 Added SYNONYM negative regulation of translation involved in gene silencing by microRNA
2010-12-01 Added DEFINITION The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2010-12-01 Deleted DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2009-09-13 Updated TERM negative regulation of translation involved in gene silencing by miRNA
2009-09-13 Added SYNONYM down regulation of translation involved in gene silencing by miRNA
2009-09-13 Added SYNONYM gene silencing by miRNA, negative regulation of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, downregulation of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, down regulation of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, inhibition of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2009-09-13 Added SYNONYM down-regulation of translation involved in gene silencing by miRNA
2009-09-13 Added SYNONYM inhibition of translation involved in gene silencing by miRNA
2009-09-13 Added SYNONYM downregulation of translation involved in gene silencing by miRNA
2008-05-13 Added DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2008-05-12 Deleted DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2008-04-01 Updated RELATION is a GO:0040033 (negative regulation of translation, ncRNA-mediated)
2008-04-01 Updated RELATION part of GO:0035195 (gene silencing by miRNA)
2008-03-06 Updated TERM gene silencing by miRNA, negative regulation of translation
2008-03-06 Added SYNONYM miRNA-mediated gene silencing, negative regulation of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, downregulation of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, inhibition of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, down regulation of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, down regulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, downregulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, inhibition of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, down regulation of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, downregulation of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, inhibition of translation
2004-12-02 Added TERM miRNA-mediated gene silencing, negative regulation of translation
2004-12-02 Added DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.

Term

Timestamp Action Category Detail
2009-09-13 Updated TERM negative regulation of translation involved in gene silencing by miRNA
2008-03-06 Updated TERM gene silencing by miRNA, negative regulation of translation
2004-12-02 Added TERM miRNA-mediated gene silencing, negative regulation of translation

Definition/synonyms

Timestamp Action Category Detail
2011-06-26 Added SYNONYM negative regulation of translation involved in gene silencing by microRNA
2010-12-01 Added DEFINITION The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2010-12-01 Deleted DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2009-09-13 Added SYNONYM down regulation of translation involved in gene silencing by miRNA
2009-09-13 Added SYNONYM gene silencing by miRNA, negative regulation of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, downregulation of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, down regulation of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, inhibition of translation
2009-09-13 Deleted SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2009-09-13 Added SYNONYM down-regulation of translation involved in gene silencing by miRNA
2009-09-13 Added SYNONYM inhibition of translation involved in gene silencing by miRNA
2009-09-13 Added SYNONYM downregulation of translation involved in gene silencing by miRNA
2008-05-13 Added DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2008-05-12 Deleted DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
2008-03-06 Added SYNONYM miRNA-mediated gene silencing, negative regulation of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, downregulation of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, inhibition of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, down regulation of translation
2007-08-09 Added SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, down regulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, downregulation of translation
2007-08-09 Deleted SYNONYM miRNA-mediated gene silencing, inhibition of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, down regulation of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, down-regulation of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, downregulation of translation
2007-02-23 Added SYNONYM miRNA-mediated gene silencing, inhibition of translation
2004-12-02 Added DEFINITION The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0040033 (negative regulation of translation, ncRNA-mediated)
2008-04-01 Updated RELATION part of GO:0035195 (gene silencing by miRNA)
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