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GO:0035102 PRC1 complex

Term Information

ID GO:0035102
Name PRC1 complex
Ontology Cellular Component
Definition A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.
PMID:10412979
Comment In Drosophila the core subunits are Pc (Polycomb), Psc (Posterior sex combs), Ph (Polyhomeotic) and Sce (Sex comb extra). In mammals, which have several orthologs for each of the Drosophila core proteins, a family of distinct PRC1-like complexes seem to exist which contain at least some PcG proteins in mutually exclusive manner.
GONUTS GO:0035102 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact Polycomb repressive complex 1

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0035102:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0035102. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0035102 based on the entire annotation set Co-occurrence statistics for GO:0035102 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-03-07 Deleted DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.
2014-03-07 Added DEFINITION A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.
2014-03-07 Added RELATION is a GO:0000152 (nuclear ubiquitin ligase complex)
2008-05-13 Added DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.
2008-05-12 Deleted DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.
2008-04-01 Updated RELATION is a GO:0031519 (PcG protein complex)
2007-08-09 Added SYNONYM Polycomb repressive complex 1
2007-08-09 Deleted SYNONYM Polycomb repressive complex 1
2004-04-19 Added SYNONYM Polycomb repressive complex 1
2004-04-16 Deleted SYNONYM Polycomb repressive complex 1
2004-02-26 Added SYNONYM Polycomb repressive complex 1
2004-02-26 Added DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.
2004-02-26 Added TERM PRC1 complex

Term

Timestamp Action Category Detail
2004-02-26 Added TERM PRC1 complex

Definition/synonyms

Timestamp Action Category Detail
2014-03-07 Deleted DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.
2014-03-07 Added DEFINITION A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.
2008-05-13 Added DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.
2008-05-12 Deleted DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.
2007-08-09 Added SYNONYM Polycomb repressive complex 1
2007-08-09 Deleted SYNONYM Polycomb repressive complex 1
2004-04-19 Added SYNONYM Polycomb repressive complex 1
2004-04-16 Deleted SYNONYM Polycomb repressive complex 1
2004-02-26 Added SYNONYM Polycomb repressive complex 1
2004-02-26 Added DEFINITION An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays.

Relationships

Timestamp Action Category Detail
2014-03-07 Added RELATION is a GO:0000152 (nuclear ubiquitin ligase complex)
2008-04-01 Updated RELATION is a GO:0031519 (PcG protein complex)
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