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GO:0034736 cholesterol O-acyltransferase activity

Term Information

ID GO:0034736
Name cholesterol O-acyltransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
GONUTS GO:0034736 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact acyl-CoA:cholesterol O-acyltransferase activity
exact acyl-CoA:cholesterol acyltransferase activity
broad cholesterol acyltransferase activity
exact cholesterol ester synthetase activity
exact cholesteryl ester synthetase activity
exact acyl coenzyme A-cholesterol-O-acyltransferase activity
broad ACAT activity
exact acylcoenzyme A:cholesterol O-acyltransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000462 GO:0034736 cholesterol O-acyltransferase activity never_in_taxon 4930 Saccharomyces
GOTAX:0000464 GO:0034736 cholesterol O-acyltransferase activity never_in_taxon 4895 Schizosaccharomyces
More information on taxon constraints in GO is available here

Cross-references

Database ID
EC 2.3.1.26
InterPro IPR030687
KEGG R01461
MetaCyc STEROL-O-ACYLTRANSFERASE-RXN
RHEA 17732

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0034736:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
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Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0034736. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0034736 based on the entire annotation set Co-occurrence statistics for GO:0034736 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: acyl-CoA + cholesterol = CoA + cholesterol ester.
2010-10-11 Added DEFINITION Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
2010-10-08 Added XREF RHEA:17732
2010-10-08 Added XREF KEGG:R01461
2009-08-23 Deleted SYNONYM cholesterol O-acyltransferase activity
2008-08-31 Added XREF EC:2.3.1.26
2008-08-31 Added TERM cholesterol O-acyltransferase activity
2008-08-31 Added DEFINITION Catalysis of the reaction: acyl-CoA + cholesterol = CoA + cholesterol ester.
2008-08-31 Added RELATION is a GO:0004772 (sterol O-acyltransferase activity)
2008-08-31 Added SYNONYM ACAT activity
2008-08-31 Added SYNONYM acyl coenzyme A-cholesterol-O-acyltransferase activity
2008-08-31 Added SYNONYM acyl-CoA:cholesterol O-acyltransferase activity
2008-08-31 Added SYNONYM acyl-CoA:cholesterol acyltransferase activity
2008-08-31 Added SYNONYM acylcoenzyme A:cholesterol O-acyltransferase activity
2008-08-31 Added SYNONYM cholesterol O-acyltransferase activity
2008-08-31 Added SYNONYM cholesterol acyltransferase activity
2008-08-31 Added SYNONYM cholesterol ester synthetase activity
2008-08-31 Added SYNONYM cholesteryl ester synthetase activity
2008-08-31 Added XREF MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN

Term

Timestamp Action Category Detail
2008-08-31 Added TERM cholesterol O-acyltransferase activity

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: acyl-CoA + cholesterol = CoA + cholesterol ester.
2010-10-11 Added DEFINITION Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
2009-08-23 Deleted SYNONYM cholesterol O-acyltransferase activity
2008-08-31 Added DEFINITION Catalysis of the reaction: acyl-CoA + cholesterol = CoA + cholesterol ester.
2008-08-31 Added SYNONYM ACAT activity
2008-08-31 Added SYNONYM acyl coenzyme A-cholesterol-O-acyltransferase activity
2008-08-31 Added SYNONYM acyl-CoA:cholesterol O-acyltransferase activity
2008-08-31 Added SYNONYM acyl-CoA:cholesterol acyltransferase activity
2008-08-31 Added SYNONYM acylcoenzyme A:cholesterol O-acyltransferase activity
2008-08-31 Added SYNONYM cholesterol O-acyltransferase activity
2008-08-31 Added SYNONYM cholesterol acyltransferase activity
2008-08-31 Added SYNONYM cholesterol ester synthetase activity
2008-08-31 Added SYNONYM cholesteryl ester synthetase activity

Relationships

Timestamp Action Category Detail
2008-08-31 Added RELATION is a GO:0004772 (sterol O-acyltransferase activity)

Cross-references

Timestamp Action Category Detail
2010-10-08 Added XREF RHEA:17732
2010-10-08 Added XREF KEGG:R01461
2008-08-31 Added XREF EC:2.3.1.26
2008-08-31 Added XREF MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN
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