spacer

GO:0034205 beta-amyloid formation

Term Information

ID GO:0034205
Name beta-amyloid formation
Ontology Biological Process
Definition The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
Comment Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because beta-amyloid can only be formed by the proteolysis of a larger molecule (see term definition). The word 'formation' is therefore used in place of biosynthesis. Also, note that this term refers to the production of the beta-amyloid polypeptide from the amyloid precursor protein (APP), and should be used to annotate e.g. secretases that cleave APP to form beta-amyloid. To annotate gene products involved in the formation of amyloid fibrils, please consider 'amyloid fibril formation' (GO:1990000).
GONUTS GO:0034205 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact beta-amyloid polypeptide formation from APP
exact beta-amyloid polypeptide formation from amyloid precursor protein

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0034205:
Relationship To GO:0034205 Child Term Child Term Name
Negatively regulates GO:1902430 negative regulation of beta-amyloid formation
Regulates GO:1902003 regulation of beta-amyloid formation
Positively regulates GO:1902004 positive regulation of beta-amyloid formation

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0034205. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0034205 based on the entire annotation set Co-occurrence statistics for GO:0034205 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-05-10 Added SYNONYM beta-amyloid polypeptide formation from amyloid precursor protein
2014-05-10 Added SYNONYM beta-amyloid polypeptide formation from APP
2008-05-13 Added DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
2008-05-12 Deleted DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
2008-04-01 Updated RELATION is a GO:0050435 (beta-amyloid metabolic process)
2008-04-01 Updated RELATION is a GO:0042987 (amyloid precursor protein catabolic process)
2008-01-27 Added DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
2008-01-21 Added TERM beta-amyloid formation

Term

Timestamp Action Category Detail
2008-01-21 Added TERM beta-amyloid formation

Definition/synonyms

Timestamp Action Category Detail
2014-05-10 Added SYNONYM beta-amyloid polypeptide formation from amyloid precursor protein
2014-05-10 Added SYNONYM beta-amyloid polypeptide formation from APP
2008-05-13 Added DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
2008-05-12 Deleted DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
2008-01-27 Added DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0050435 (beta-amyloid metabolic process)
2008-04-01 Updated RELATION is a GO:0042987 (amyloid precursor protein catabolic process)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
11ms