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GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity

Catalysis of the reaction: endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.

Term Information

ID GO:0033925
Name mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
Ontology Molecular Function
Definition Catalysis of the reaction: endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.
Comment

Synonyms

Type Synonym
exact glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity
exact mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity
exact mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity
exact endo-beta-N-acetylglucosaminidase activity
exact endoglycosidase S activity
exact glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity
exact endo-beta-acetylglucosaminidase activity
exact endoglycosidase H activity
exact N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity
exact di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity
exact endo-N-acetyl-beta-D-glucosaminidase activity
exact endo-N-acetyl-beta-glucosaminidase activity
exact endo-beta-(1->4)-N-acetylglucosaminidase activity
exact endo-beta-N-acetylglucosaminidase D activity
exact endo-beta-N-acetylglucosaminidase F activity
exact endo-beta-N-acetylglucosaminidase H activity
exact endo-beta-N-acetylglucosaminidase L activity

Cross-references associated with this term:

Database ID
INTERPRO IPR005201
INTERPRO IPR016289
EC 3.2.1.96
MetaCyc 3.2.1.96-RXN

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
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Taxonomy
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Co-occurring Terms

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