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GO:0033777 lithocholate 6beta-hydroxylase activity

Term Information

ID GO:0033777
Name lithocholate 6beta-hydroxylase activity
Ontology Molecular Function
Definition Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).
GONUTS GO:0033777 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad 6beta-hydroxylase activity
related CYP3A10
exact cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity
exact lithocholate 6beta-monooxygenase activity
exact lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.14.13.94
KEGG R07203
MetaCyc 1.14.13.94-RXN
RHEA 18860

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0033777:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0033777. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0033777 based on the entire annotation set Co-occurrence statistics for GO:0033777 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2010-10-11 Added DEFINITION Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).
2010-10-11 Added XREF RHEA:18860
2010-10-11 Added XREF KEGG:R07203
2009-05-21 Added XREF MetaCyc:1.14.13.94-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2008-04-01 Added SYNONYM 6beta-hydroxylase activity
2008-04-01 Deleted SYNONYM 6beta-hydroxylase activity
2008-04-01 Deleted SYNONYM lithocholate 6beta-hydroxylase activity
2008-04-01 Updated RELATION is a GO:0016709 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen)
2007-11-27 Added DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2007-11-08 Added TERM lithocholate 6beta-hydroxylase activity
2007-11-08 Added SYNONYM 6beta-hydroxylase activity
2007-11-08 Added SYNONYM CYP3A10
2007-11-08 Added SYNONYM cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity
2007-11-08 Added SYNONYM lithocholate 6beta-hydroxylase activity
2007-11-08 Added SYNONYM lithocholate 6beta-monooxygenase activity
2007-11-08 Added SYNONYM lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity
2007-11-08 Added XREF EC:1.14.13.94

Term

Timestamp Action Category Detail
2007-11-08 Added TERM lithocholate 6beta-hydroxylase activity

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2010-10-11 Added DEFINITION Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).
2008-05-13 Added DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2008-04-01 Added SYNONYM 6beta-hydroxylase activity
2008-04-01 Deleted SYNONYM 6beta-hydroxylase activity
2008-04-01 Deleted SYNONYM lithocholate 6beta-hydroxylase activity
2007-11-27 Added DEFINITION Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O.
2007-11-08 Added SYNONYM 6beta-hydroxylase activity
2007-11-08 Added SYNONYM CYP3A10
2007-11-08 Added SYNONYM cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity
2007-11-08 Added SYNONYM lithocholate 6beta-hydroxylase activity
2007-11-08 Added SYNONYM lithocholate 6beta-monooxygenase activity
2007-11-08 Added SYNONYM lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016709 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:18860
2010-10-11 Added XREF KEGG:R07203
2009-05-21 Added XREF MetaCyc:1.14.13.94-RXN
2007-11-08 Added XREF EC:1.14.13.94
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