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GO:0033673 negative regulation of kinase activity

Term Information

ID GO:0033673
Name negative regulation of kinase activity
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GONUTS GO:0033673 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact down regulation of kinase activity
exact down-regulation of kinase activity
exact downregulation of kinase activity
narrow inhibition of kinase activity
narrow kinase inhibitor

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0033673:
Relationship To GO:0033673 Child Term Child Term Name
Is a GO:0006469 negative regulation of protein kinase activity
Is a GO:0033671 negative regulation of NAD+ kinase activity
Is a GO:0090219 negative regulation of lipid kinase activity
Is a GO:1903300 negative regulation of hexokinase activity
Is a GO:1903303 negative regulation of pyruvate kinase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0033673. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0033673 based on the entire annotation set Co-occurrence statistics for GO:0033673 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-10-18 Added RELATION is a GO:0042326 (negative regulation of phosphorylation)
2010-06-15 Added RELATION negatively regulates GO:0016301 (kinase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0016301 (kinase activity)
2010-06-09 Updated TERM negative regulation of kinase activity
2010-06-08 Added RELATION negatively regulates GO:0016301 (kinase activity)
2010-06-08 Updated TERM negative regulation of kinase activity
2009-02-25 Updated TERM negative regulation of kinase activity
2009-02-25 Deleted RELATION negatively regulates GO:0016301 (kinase activity)
2009-02-22 Added RELATION negatively regulates GO:0016301 (kinase activity)
2009-02-22 Updated TERM negative regulation of kinase activity
2008-05-13 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
2008-05-12 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
2008-04-01 Updated RELATION is a GO:0051348 (negative regulation of transferase activity)
2008-04-01 Updated RELATION is a GO:0043549 (regulation of kinase activity)
2007-10-25 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
2007-10-18 Added SYNONYM down regulation of kinase activity
2007-10-18 Added SYNONYM down-regulation of kinase activity
2007-10-18 Added SYNONYM downregulation of kinase activity
2007-10-18 Added SYNONYM inhibition of kinase activity
2007-10-18 Added SYNONYM kinase inhibitor
2007-10-18 Added TERM negative regulation of kinase activity

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM negative regulation of kinase activity
2010-06-08 Updated TERM negative regulation of kinase activity
2009-02-25 Updated TERM negative regulation of kinase activity
2009-02-22 Updated TERM negative regulation of kinase activity
2007-10-18 Added TERM negative regulation of kinase activity

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
2008-05-12 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
2007-10-25 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
2007-10-18 Added SYNONYM down regulation of kinase activity
2007-10-18 Added SYNONYM down-regulation of kinase activity
2007-10-18 Added SYNONYM downregulation of kinase activity
2007-10-18 Added SYNONYM inhibition of kinase activity
2007-10-18 Added SYNONYM kinase inhibitor

Relationships

Timestamp Action Category Detail
2014-10-18 Added RELATION is a GO:0042326 (negative regulation of phosphorylation)
2010-06-15 Added RELATION negatively regulates GO:0016301 (kinase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0016301 (kinase activity)
2010-06-08 Added RELATION negatively regulates GO:0016301 (kinase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0016301 (kinase activity)
2009-02-22 Added RELATION negatively regulates GO:0016301 (kinase activity)
2008-04-01 Updated RELATION is a GO:0051348 (negative regulation of transferase activity)
2008-04-01 Updated RELATION is a GO:0043549 (regulation of kinase activity)
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