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GO:0032865 ERMES complex

Term Information

ID GO:0032865
Name ERMES complex
Ontology Cellular Component
Definition A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth.
PMID:19556461
GONUTS GO:0032865 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact Mdm10/Mdm12/Mmm1 complex
exact ER-mitochondria encounter structure
exact mitochore
exact MMM1 complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005623 cell only_in_taxon 131567 cellular organisms
GO:0005739 mitochondrion only_in_taxon 2759 Eukaryota
GO:0005783 endoplasmic reticulum only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR027532
InterPro IPR027536
InterPro IPR027537
InterPro IPR027539

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0032865:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0032865. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0032865 based on the entire annotation set Co-occurrence statistics for GO:0032865 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0044455 (mitochondrial membrane part)
2015-06-25 Deleted RELATION is a GO:0043234 (protein complex)
2015-05-11 Added RELATION is a GO:0098799 (outer mitochondrial membrane protein complex)
2011-02-15 Added SYNONYM MMM1 complex
2011-02-15 Added SYNONYM mitochore
2010-10-11 Added RELATION is a GO:0044432 (endoplasmic reticulum part)
2010-01-14 Updated TERM ERMES complex
2010-01-14 Deleted DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2010-01-14 Added DEFINITION A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth.
2010-01-14 Added SYNONYM ER-mitochondria encounter structure
2010-01-14 Added SYNONYM Mdm10/Mdm12/Mmm1 complex
2010-01-14 Added RELATION part of GO:0044233 (ER-mitochondrion membrane contact site)
2008-05-13 Added DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2008-05-12 Deleted DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2008-04-01 Updated RELATION part of GO:0005741 (mitochondrial outer membrane)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044455 (mitochondrial membrane part)
2007-02-06 Added DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2007-02-05 Added TERM Mdm10/Mdm12/Mmm1 complex

Term

Timestamp Action Category Detail
2010-01-14 Updated TERM ERMES complex
2007-02-05 Added TERM Mdm10/Mdm12/Mmm1 complex

Definition/synonyms

Timestamp Action Category Detail
2011-02-15 Added SYNONYM MMM1 complex
2011-02-15 Added SYNONYM mitochore
2010-01-14 Deleted DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2010-01-14 Added DEFINITION A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth.
2010-01-14 Added SYNONYM ER-mitochondria encounter structure
2010-01-14 Added SYNONYM Mdm10/Mdm12/Mmm1 complex
2008-05-13 Added DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2008-05-12 Deleted DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2007-02-06 Added DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.

Relationships

Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0044455 (mitochondrial membrane part)
2015-06-25 Deleted RELATION is a GO:0043234 (protein complex)
2015-05-11 Added RELATION is a GO:0098799 (outer mitochondrial membrane protein complex)
2010-10-11 Added RELATION is a GO:0044432 (endoplasmic reticulum part)
2010-01-14 Added RELATION part of GO:0044233 (ER-mitochondrion membrane contact site)
2008-04-01 Updated RELATION part of GO:0005741 (mitochondrial outer membrane)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044455 (mitochondrial membrane part)
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