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GO:0032720 negative regulation of tumor necrosis factor production

Term Information

ID GO:0032720
Name negative regulation of tumor necrosis factor production
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
Comment Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').
GONUTS GO:0032720 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact down regulation of tumor necrosis factor production
exact negative regulation TNF production
exact negative regulation TNF-alpha production
exact negative regulation tumor necrosis factor-alpha production
exact downregulation of tumor necrosis factor production
exact down-regulation of tumor necrosis factor production
narrow inhibition of tumor necrosis factor production

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to terms describing protein or chemical productionLink

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0032720:
Relationship To GO:0032720 Child Term Child Term Name
Is a GO:0042536 negative regulation of tumor necrosis factor biosynthetic process

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0032720. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0032720 based on the entire annotation set Co-occurrence statistics for GO:0032720 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-10-23 Added RELATION is a GO:1903556 (negative regulation of tumor necrosis factor superfamily cytokine production)
2014-10-23 Deleted RELATION is a GO:0001818 (negative regulation of cytokine production)
2008-05-13 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
2008-05-12 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
2008-04-01 Updated RELATION is a GO:0032680 (regulation of tumor necrosis factor production)
2008-04-01 Updated RELATION is a GO:0001818 (negative regulation of cytokine production)
2008-04-01 Added RELATION negatively regulates GO:0032640 (tumor necrosis factor production)
2007-08-09 Added SYNONYM down regulation of tumor necrosis factor production
2007-08-09 Added SYNONYM down-regulation of tumor necrosis factor production
2007-08-09 Added SYNONYM downregulation of tumor necrosis factor production
2007-08-09 Added SYNONYM inhibition of tumor necrosis factor production
2007-08-09 Added SYNONYM negative regulation TNF production
2007-08-09 Added SYNONYM negative regulation TNF-alpha production
2007-08-09 Added SYNONYM negative regulation tumor necrosis factor-alpha production
2007-08-09 Deleted SYNONYM down regulation of tumor necrosis factor production
2007-08-09 Deleted SYNONYM down-regulation of tumor necrosis factor production
2007-08-09 Deleted SYNONYM downregulation of tumor necrosis factor production
2007-08-09 Deleted SYNONYM inhibition of tumor necrosis factor production
2007-08-09 Deleted SYNONYM negative regulation TNF production
2007-08-09 Deleted SYNONYM negative regulation TNF-alpha production
2007-08-09 Deleted SYNONYM negative regulation tumor necrosis factor-alpha production
2007-03-06 Updated DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
2007-03-04 Added SYNONYM down regulation of tumor necrosis factor production
2007-03-04 Added SYNONYM down-regulation of tumor necrosis factor production
2007-03-04 Added SYNONYM downregulation of tumor necrosis factor production
2007-03-04 Added SYNONYM inhibition of tumor necrosis factor production
2007-03-04 Added SYNONYM negative regulation TNF production
2007-03-04 Added SYNONYM negative regulation TNF-alpha production
2007-03-04 Added SYNONYM negative regulation tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM down regulation of tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM down-regulation of tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM downregulation of tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM inhibition of tumor necrosis factor-alpha production
2007-03-04 Updated TERM negative regulation of tumor necrosis factor production
2007-02-23 Added SYNONYM down regulation of tumor necrosis factor-alpha production
2007-02-23 Added SYNONYM down-regulation of tumor necrosis factor-alpha production
2007-02-23 Added SYNONYM downregulation of tumor necrosis factor-alpha production
2007-02-23 Added SYNONYM inhibition of tumor necrosis factor-alpha production
2006-12-06 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor-alpha production.
2006-12-06 Added TERM negative regulation of tumor necrosis factor-alpha production

Term

Timestamp Action Category Detail
2007-03-04 Updated TERM negative regulation of tumor necrosis factor production
2006-12-06 Added TERM negative regulation of tumor necrosis factor-alpha production

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
2008-05-12 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
2007-08-09 Added SYNONYM down regulation of tumor necrosis factor production
2007-08-09 Added SYNONYM down-regulation of tumor necrosis factor production
2007-08-09 Added SYNONYM downregulation of tumor necrosis factor production
2007-08-09 Added SYNONYM inhibition of tumor necrosis factor production
2007-08-09 Added SYNONYM negative regulation TNF production
2007-08-09 Added SYNONYM negative regulation TNF-alpha production
2007-08-09 Added SYNONYM negative regulation tumor necrosis factor-alpha production
2007-08-09 Deleted SYNONYM down regulation of tumor necrosis factor production
2007-08-09 Deleted SYNONYM down-regulation of tumor necrosis factor production
2007-08-09 Deleted SYNONYM downregulation of tumor necrosis factor production
2007-08-09 Deleted SYNONYM inhibition of tumor necrosis factor production
2007-08-09 Deleted SYNONYM negative regulation TNF production
2007-08-09 Deleted SYNONYM negative regulation TNF-alpha production
2007-08-09 Deleted SYNONYM negative regulation tumor necrosis factor-alpha production
2007-03-06 Updated DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
2007-03-04 Added SYNONYM down regulation of tumor necrosis factor production
2007-03-04 Added SYNONYM down-regulation of tumor necrosis factor production
2007-03-04 Added SYNONYM downregulation of tumor necrosis factor production
2007-03-04 Added SYNONYM inhibition of tumor necrosis factor production
2007-03-04 Added SYNONYM negative regulation TNF production
2007-03-04 Added SYNONYM negative regulation TNF-alpha production
2007-03-04 Added SYNONYM negative regulation tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM down regulation of tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM down-regulation of tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM downregulation of tumor necrosis factor-alpha production
2007-03-04 Deleted SYNONYM inhibition of tumor necrosis factor-alpha production
2007-02-23 Added SYNONYM down regulation of tumor necrosis factor-alpha production
2007-02-23 Added SYNONYM down-regulation of tumor necrosis factor-alpha production
2007-02-23 Added SYNONYM downregulation of tumor necrosis factor-alpha production
2007-02-23 Added SYNONYM inhibition of tumor necrosis factor-alpha production
2006-12-06 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor-alpha production.

Relationships

Timestamp Action Category Detail
2014-10-23 Added RELATION is a GO:1903556 (negative regulation of tumor necrosis factor superfamily cytokine production)
2014-10-23 Deleted RELATION is a GO:0001818 (negative regulation of cytokine production)
2008-04-01 Updated RELATION is a GO:0032680 (regulation of tumor necrosis factor production)
2008-04-01 Updated RELATION is a GO:0001818 (negative regulation of cytokine production)
2008-04-01 Added RELATION negatively regulates GO:0032640 (tumor necrosis factor production)
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