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GO:0045892 negative regulation of transcription, DNA-templated

Term Information

ID GO:0045892
Name negative regulation of transcription, DNA-templated
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
Secondary IDs GO:0016481 GO:0032582 GO:0061021
GONUTS GO:0045892 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative regulation of cellular transcription, DNA-dependent
exact negative regulation of transcription, DNA-dependent
related transcription repressor activity
related negative regulation of gene-specific transcription
narrow inhibition of transcription, DNA-dependent
related down regulation of gene-specific transcription
related down-regulation of gene-specific transcription
related downregulation of gene-specific transcription
exact downregulation of transcription, DNA-dependent
exact down-regulation of transcription, DNA-dependent
exact down regulation of transcription, DNA-dependent
related inhibition of gene-specific transcription

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to transcription processesLink

Cross-references

Database ID
InterPro IPR003012
InterPro IPR003796
InterPro IPR004111
InterPro IPR005650
InterPro IPR006942
InterPro IPR006986
InterPro IPR006988
InterPro IPR006989
InterPro IPR007412
InterPro IPR008468
InterPro IPR009718
InterPro IPR010078
InterPro IPR010089
InterPro IPR010193
InterPro IPR010194
InterPro IPR010248
InterPro IPR010405
InterPro IPR010575
InterPro IPR010712
InterPro IPR010744
InterPro IPR011797
InterPro IPR012712
InterPro IPR012771
InterPro IPR013571
InterPro IPR013573
InterPro IPR014154
InterPro IPR015309
InterPro IPR016429
InterPro IPR017275
InterPro IPR020890
InterPro IPR022876
InterPro IPR023711
InterPro IPR023731
InterPro IPR023761
InterPro IPR026052
InterPro IPR026271
InterPro IPR026668
InterPro IPR026810
InterPro IPR028734

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0016564 transcription repressor activity CONSIDER GO:0045892
GO:0016565 general transcriptional repressor activity CONSIDER GO:0045892
GO:0016566 specific transcriptional repressor activity CONSIDER GO:0045892
GO:0017163 basal transcription repressor activity CONSIDER GO:0045892

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045892:
Relationship To GO:0045892 Child Term Child Term Name
Is a GO:0000122 negative regulation of transcription from RNA polymerase II promoter
Is a GO:0007068 negative regulation of transcription during mitosis
Is a GO:0016479 negative regulation of transcription from RNA polymerase I promoter
Is a GO:0016480 negative regulation of transcription from RNA polymerase III promoter
Is a GO:0045013 carbon catabolite repression of transcription
Is a GO:0045894 negative regulation of mating-type specific transcription, DNA-templated
Is a GO:0051038 negative regulation of transcription during meiosis
Is a GO:0045996 negative regulation of transcription by pheromones
Is a GO:0006342 chromatin silencing
Is a GO:0060567 negative regulation of DNA-templated transcription, termination
Is a GO:0010621 negative regulation of transcription by transcription factor localization
Is a GO:0090295 nitrogen catabolite repression of transcription
Is a GO:0010944 negative regulation of transcription by competitive promoter binding
Is a GO:0060195 negative regulation of antisense RNA transcription
Is a GO:2000143 negative regulation of DNA-templated transcription, initiation
Is a GO:0097549 negative regulation of transcription by chromatin organization
Is a GO:0010620 negative regulation of transcription by transcription factor catabolism
Is a GO:0010678 negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated
Part of GO:0001210 metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
Part of GO:0001217 sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0045892. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0045892 based on the entire annotation set Co-occurrence statistics for GO:0045892 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-02-07 Added RELATION is a GO:1902679 (negative regulation of RNA biosynthetic process)
2014-02-07 Deleted RELATION is a GO:0051253 (negative regulation of RNA metabolic process)
2013-12-14 Updated TERM negative regulation of transcription, DNA-templated
2013-12-14 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2013-12-14 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2013-12-14 Added SYNONYM negative regulation of transcription, DNA-dependent
2011-11-17 Added SYNONYM transcription repressor activity
2011-05-15 Added SECONDARY GO:0032582 (negative regulation of gene-specific transcription)
2011-05-15 Added SYNONYM down regulation of gene-specific transcription
2011-05-15 Added SYNONYM downregulation of gene-specific transcription
2011-05-15 Added SYNONYM negative regulation of gene-specific transcription
2011-05-15 Added SYNONYM inhibition of gene-specific transcription
2011-05-15 Added SYNONYM down-regulation of gene-specific transcription
2011-03-18 Added SECONDARY GO:0061021 (negative regulation of transcription)
2011-03-18 Added SECONDARY GO:0016481 (negative regulation of transcription)
2011-03-18 Added RELATION is a GO:2000113 (negative regulation of cellular macromolecule biosynthetic process)
2011-03-18 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2011-03-18 Deleted RELATION is a GO:0016481 (negative regulation of transcription)
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2010-02-27 Updated TERM negative regulation of transcription, DNA-dependent
2010-02-27 Added SYNONYM negative regulation of cellular transcription, DNA-dependent
2010-02-10 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2010-02-10 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2010-02-10 Updated TERM negative regulation of cellular transcription, DNA-dependent
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2008-04-01 Updated RELATION is a GO:0051253 (negative regulation of RNA metabolic process)
2008-04-01 Updated RELATION is a GO:0016481 (negative regulation of transcription)
2008-04-01 Updated RELATION is a GO:0006355 (regulation of transcription, DNA-templated)
2008-04-01 Added RELATION negatively regulates GO:0006351 (transcription, DNA-templated)
2007-08-09 Added SYNONYM down regulation of transcription, DNA-dependent
2007-08-09 Added SYNONYM down-regulation of transcription, DNA-dependent
2007-08-09 Added SYNONYM downregulation of transcription, DNA-dependent
2007-08-09 Added SYNONYM inhibition of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM down regulation of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM down-regulation of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM downregulation of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM inhibition of transcription, DNA-dependent
2007-02-23 Added SYNONYM down regulation of transcription, DNA-dependent
2007-02-23 Added SYNONYM down-regulation of transcription, DNA-dependent
2007-02-23 Added SYNONYM downregulation of transcription, DNA-dependent
2007-02-23 Added SYNONYM inhibition of transcription, DNA-dependent
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of DNA-dependent transcription.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of DNA-dependent transcription.
2002-08-20 Added TERM negative regulation of transcription, DNA-dependent

Term

Timestamp Action Category Detail
2013-12-14 Updated TERM negative regulation of transcription, DNA-templated
2010-02-27 Updated TERM negative regulation of transcription, DNA-dependent
2010-02-10 Updated TERM negative regulation of cellular transcription, DNA-dependent
2002-08-20 Added TERM negative regulation of transcription, DNA-dependent

Definition/synonyms

Timestamp Action Category Detail
2013-12-14 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2013-12-14 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2013-12-14 Added SYNONYM negative regulation of transcription, DNA-dependent
2011-11-17 Added SYNONYM transcription repressor activity
2011-05-15 Added SYNONYM down regulation of gene-specific transcription
2011-05-15 Added SYNONYM downregulation of gene-specific transcription
2011-05-15 Added SYNONYM negative regulation of gene-specific transcription
2011-05-15 Added SYNONYM inhibition of gene-specific transcription
2011-05-15 Added SYNONYM down-regulation of gene-specific transcription
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2010-02-27 Added SYNONYM negative regulation of cellular transcription, DNA-dependent
2010-02-10 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
2010-02-10 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2007-08-09 Added SYNONYM down regulation of transcription, DNA-dependent
2007-08-09 Added SYNONYM down-regulation of transcription, DNA-dependent
2007-08-09 Added SYNONYM downregulation of transcription, DNA-dependent
2007-08-09 Added SYNONYM inhibition of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM down regulation of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM down-regulation of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM downregulation of transcription, DNA-dependent
2007-08-09 Deleted SYNONYM inhibition of transcription, DNA-dependent
2007-02-23 Added SYNONYM down regulation of transcription, DNA-dependent
2007-02-23 Added SYNONYM down-regulation of transcription, DNA-dependent
2007-02-23 Added SYNONYM downregulation of transcription, DNA-dependent
2007-02-23 Added SYNONYM inhibition of transcription, DNA-dependent
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of DNA-dependent transcription.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of DNA-dependent transcription.

Relationships

Timestamp Action Category Detail
2014-02-07 Added RELATION is a GO:1902679 (negative regulation of RNA biosynthetic process)
2014-02-07 Deleted RELATION is a GO:0051253 (negative regulation of RNA metabolic process)
2011-03-18 Added RELATION is a GO:2000113 (negative regulation of cellular macromolecule biosynthetic process)
2011-03-18 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2011-03-18 Deleted RELATION is a GO:0016481 (negative regulation of transcription)
2008-04-01 Updated RELATION is a GO:0051253 (negative regulation of RNA metabolic process)
2008-04-01 Updated RELATION is a GO:0016481 (negative regulation of transcription)
2008-04-01 Updated RELATION is a GO:0006355 (regulation of transcription, DNA-templated)
2008-04-01 Added RELATION negatively regulates GO:0006351 (transcription, DNA-templated)

Other

Timestamp Action Category Detail
2011-05-15 Added SECONDARY GO:0032582 (negative regulation of gene-specific transcription)
2011-03-18 Added SECONDARY GO:0061021 (negative regulation of transcription)
2011-03-18 Added SECONDARY GO:0016481 (negative regulation of transcription)
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