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GO:0031932 TORC2 complex

Term Information

ID GO:0031932
Name TORC2 complex
Ontology Cellular Component
Definition A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.
PMID:14736892 PMID:15780592 PMID:16469695 PMID:21548787
GONUTS GO:0031932 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact rapamycin and nutrient-insensitive TOR complex
narrow mTORC2
exact TORC2
exact TOR complex 2
exact TORC 2 complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Protein complexes

Database ID Name
IntAct torc2_yeast TORC2 complex

Cross-references

Database ID
InterPro IPR028268
Wikipedia MTORC1

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0031932:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0031932. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0031932 based on the entire annotation set Co-occurrence statistics for GO:0031932 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-11 Added XREF Wikipedia:MTORC1
2013-12-11 Added RELATION is a GO:0038201 (TOR complex)
2013-12-11 Deleted RELATION is a GO:0044424 (intracellular part)
2011-11-24 Added SYNONYM TORC2
2011-11-24 Added SYNONYM mTORC2
2011-11-24 Added SYNONYM rapamycin and nutrient-insensitive TOR complex
2011-11-24 Deleted DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization. In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p; in mammals the complex contains orthologs of the yeast proteins.
2011-11-24 Added DEFINITION A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.
2009-02-25 Added DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization. In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p; in mammals the complex contains orthologs of the yeast proteins.
2009-02-25 Deleted DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2009-02-25 Added SYNONYM TOR complex 2
2008-05-13 Added DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2008-05-12 Deleted DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044424 (intracellular part)
2008-01-07 Added SYNONYM TORC 2 complex
2008-01-07 Updated TERM TORC2 complex
2005-11-30 Updated DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2005-11-28 Added DEFINITION protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2005-11-28 Added TERM TORC 2 complex

Term

Timestamp Action Category Detail
2008-01-07 Updated TERM TORC2 complex
2005-11-28 Added TERM TORC 2 complex

Definition/synonyms

Timestamp Action Category Detail
2011-11-24 Added SYNONYM TORC2
2011-11-24 Added SYNONYM mTORC2
2011-11-24 Added SYNONYM rapamycin and nutrient-insensitive TOR complex
2011-11-24 Deleted DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization. In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p; in mammals the complex contains orthologs of the yeast proteins.
2011-11-24 Added DEFINITION A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.
2009-02-25 Added DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization. In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p; in mammals the complex contains orthologs of the yeast proteins.
2009-02-25 Deleted DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2009-02-25 Added SYNONYM TOR complex 2
2008-05-13 Added DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2008-05-12 Deleted DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2008-01-07 Added SYNONYM TORC 2 complex
2005-11-30 Updated DEFINITION A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.
2005-11-28 Added DEFINITION protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization.

Relationships

Timestamp Action Category Detail
2013-12-11 Added RELATION is a GO:0038201 (TOR complex)
2013-12-11 Deleted RELATION is a GO:0044424 (intracellular part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044424 (intracellular part)

Cross-references

Timestamp Action Category Detail
2013-12-11 Added XREF Wikipedia:MTORC1
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