spacer

GO:0031663 lipopolysaccharide-mediated signaling pathway

Term Information

ID GO:0031663
Name lipopolysaccharide-mediated signaling pathway
Ontology Biological Process
Definition A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
PMID:15379975
GONUTS GO:0031663 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact LPS-mediated signaling pathway
exact lipopolysaccharide-mediated signalling pathway

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating gene products that interact with other organisms Link

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR027168

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0031663:
Relationship To GO:0031663 Child Term Child Term Name
Regulates GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway
Negatively regulates GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway
Positively regulates GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
Part of GO:0001875 lipopolysaccharide receptor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0031663. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0031663 based on the entire annotation set Co-occurrence statistics for GO:0031663 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-01-18 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
2010-05-16 Added RELATION is a GO:0071222 (cellular response to lipopolysaccharide)
2010-05-06 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
2010-05-06 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immue system.
2010-04-14 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.
2010-04-14 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immue system.
2010-04-14 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-20 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2008-05-13 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.
2008-05-12 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.
2008-04-01 Updated RELATION is a GO:0007166 (cell surface receptor signaling pathway)
2007-12-21 Added SYNONYM LPS-mediated signaling pathway
2007-08-09 Added SYNONYM lipopolysaccharide-mediated signalling pathway
2007-08-09 Deleted SYNONYM lipopolysaccharide-mediated signalling pathway
2005-10-15 Added TERM lipopolysaccharide-mediated signaling pathway
2005-10-15 Added SYNONYM lipopolysaccharide-mediated signalling pathway
2005-10-15 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.

Term

Timestamp Action Category Detail
2005-10-15 Added TERM lipopolysaccharide-mediated signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2012-01-18 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
2012-01-18 Added DEFINITION A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
2010-05-06 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
2010-05-06 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immue system.
2010-04-14 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.
2010-04-14 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immue system.
2008-05-13 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.
2008-05-12 Deleted DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.
2007-12-21 Added SYNONYM LPS-mediated signaling pathway
2007-08-09 Added SYNONYM lipopolysaccharide-mediated signalling pathway
2007-08-09 Deleted SYNONYM lipopolysaccharide-mediated signalling pathway
2005-10-15 Added SYNONYM lipopolysaccharide-mediated signalling pathway
2005-10-15 Added DEFINITION The series of molecular signals generated in response to detection of lipopolysaccharide.

Relationships

Timestamp Action Category Detail
2010-05-16 Added RELATION is a GO:0071222 (cellular response to lipopolysaccharide)
2010-04-14 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-20 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2008-04-01 Updated RELATION is a GO:0007166 (cell surface receptor signaling pathway)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
12ms