spacer
spacer

GO:0031623 receptor internalization

The process by which cell surface receptors are monoubiquitinated following ligand-induced activation, and subsequently taken up into endocytic vesicles and targeted to the lysosome or vacuole for degradation; serves as a mechanism to downregulate receptor signaling.

Term Information

ID GO:0031623
Name receptor internalization
Ontology Biological Process
Definition The process by which cell surface receptors are monoubiquitinated following ligand-induced activation, and subsequently taken up into endocytic vesicles and targeted to the lysosome or vacuole for degradation; serves as a mechanism to downregulate receptor signaling.
Comment

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0016043 cellular component organization
GO:0051179 localization
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0043170 macromolecule metabolic process
GO:0051234 establishment of localization
GO:0006810 transport
GO:0016044 membrane organization
GO:0044237 cellular metabolic process
GO:0010324 membrane invagination
GO:0044260 cellular macromolecule metabolic process
GO:0016192 vesicle-mediated transport
GO:0043112 receptor metabolic process
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0031623 receptor internalization

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0002031 G-protein coupled receptor internalization
R GO:0002090 regulation of receptor internalization
NR GO:0002091 negative regulation of receptor internalization
PR GO:0002092 positive regulation of receptor internalization

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
spacer
11ms
spacer