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GO:0031499 TRAMP complex

Term Information

ID GO:0031499
Name TRAMP complex
Ontology Cellular Component
Definition A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
PMID:15173578 PMID:15828860 PMID:15935758 PMID:15935759 PMID:16373491 PMID:16374505 PMID:16431988 PMID:16973437 PMID:17410208 PMID:17652137
GONUTS GO:0031499 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow Trf4 complex
narrow Trf4 poly(A) polymerase complex
narrow TRAMP5 complex
narrow Trf4p-Air2p-Mtr4p polyadenylation complex
narrow TRAMP4 complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Protein complexes

Database ID Name
IntAct tramp_yeast-1 TRAMP complex variant 1
IntAct tramp_yeast-2 TRAMP complex variant 2

Cross-references

Database ID
Wikipedia TRAMP_complex

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0031499:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
Evidence
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0031499. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0031499 based on the entire annotation set Co-occurrence statistics for GO:0031499 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-07-30 Deleted SYNONYM Trf4 complex
2009-07-30 Deleted DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2009-07-30 Added DEFINITION A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
2009-07-30 Deleted SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2009-07-30 Deleted SYNONYM Trf4 poly(A) polymerase complex
2009-07-30 Added SYNONYM TRAMP5 complex
2009-07-30 Added SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2009-07-30 Added SYNONYM Trf4 complex
2009-07-30 Added SYNONYM Trf4 poly(A) polymerase complex
2009-07-30 Added SYNONYM TRAMP4 complex
2009-02-08 Added XREF Wikipedia:TRAMP_complex
2008-05-13 Added DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2008-05-12 Deleted DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044428 (nuclear part)
2007-08-09 Added SYNONYM Trf4 complex
2007-08-09 Added SYNONYM Trf4 poly(A) polymerase complex
2007-08-09 Added SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2007-08-09 Deleted SYNONYM Trf4 complex
2007-08-09 Deleted SYNONYM Trf4 poly(A) polymerase complex
2007-08-09 Deleted SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2005-06-21 Added DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2005-06-20 Added TERM TRAMP complex
2005-06-20 Added SYNONYM Trf4 complex
2005-06-20 Added SYNONYM Trf4 poly(A) polymerase complex
2005-06-20 Added SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex

Term

Timestamp Action Category Detail
2005-06-20 Added TERM TRAMP complex

Definition/synonyms

Timestamp Action Category Detail
2009-07-30 Deleted SYNONYM Trf4 complex
2009-07-30 Deleted DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2009-07-30 Added DEFINITION A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
2009-07-30 Deleted SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2009-07-30 Deleted SYNONYM Trf4 poly(A) polymerase complex
2009-07-30 Added SYNONYM TRAMP5 complex
2009-07-30 Added SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2009-07-30 Added SYNONYM Trf4 complex
2009-07-30 Added SYNONYM Trf4 poly(A) polymerase complex
2009-07-30 Added SYNONYM TRAMP4 complex
2008-05-13 Added DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2008-05-12 Deleted DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2007-08-09 Added SYNONYM Trf4 complex
2007-08-09 Added SYNONYM Trf4 poly(A) polymerase complex
2007-08-09 Added SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2007-08-09 Deleted SYNONYM Trf4 complex
2007-08-09 Deleted SYNONYM Trf4 poly(A) polymerase complex
2007-08-09 Deleted SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex
2005-06-21 Added DEFINITION A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo.
2005-06-20 Added SYNONYM Trf4 complex
2005-06-20 Added SYNONYM Trf4 poly(A) polymerase complex
2005-06-20 Added SYNONYM Trf4p-Air2p-Mtr4p polyadenylation complex

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044428 (nuclear part)

Cross-references

Timestamp Action Category Detail
2009-02-08 Added XREF Wikipedia:TRAMP_complex
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