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GO:0031264 death-inducing signaling complexA protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor.
Term Information
GO SlimsThis term is present in the following GO Consortium-maintained GO slims:
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| Type | Synonym |
| exact | death-inducing signalling complex |
| exact | DISC |
| Database | ID |
| Wikipedia | Death-inducing_signaling_complex |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0005575 cellular_component | |||||||||
![]() | GO:0005623 cell | ||||||||
![]() | ![]() | GO:0032991 macromolecular complex | |||||||
![]() | ![]() | ![]() | GO:0043234 protein complex | ||||||
![]() | ![]() | ![]() | ![]() | GO:0044464 cell part | |||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016020 membrane | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0005886 plasma membrane | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044425 membrane part | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044459 plasma membrane part | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0031264 death-inducing signaling complex |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0031265 CD95 death-inducing signaling complex |
| I | GO:0031266 TRAIL death-inducing signaling complex |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-12-16-04-01-54 |