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GO:0030976 thiamine pyrophosphate binding

Term Information

ID GO:0030976
Name thiamine pyrophosphate binding
Ontology Molecular Function
Definition Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
GONUTS GO:0030976 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact cocarboxylase binding
exact diphosphothiamin binding
exact thiamin pyrophosphate binding
exact aneurine pyrophosphate binding
exact TPP binding

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Binding term considerationsLink

Cross-Ontology Relations

Relation Other Ontology ID Term
has_input CHEBI CHEBI:45931 thiamine(1+) diphosphate(1-)

Cross-references

Database ID
InterPro IPR000399
InterPro IPR004433
InterPro IPR011603
InterPro IPR011766
InterPro IPR012000
InterPro IPR012001
InterPro IPR012782
InterPro IPR012846
InterPro IPR017660
InterPro IPR017820
InterPro IPR022494
InterPro IPR022502
InterPro IPR023757

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030976:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030976. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030976 based on the entire annotation set Co-occurrence statistics for GO:0030976 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-12-05 Added RELATION is a GO:1901681 (sulfur compound binding)
2012-09-19 Added RELATION is a GO:1901363 (heterocyclic compound binding)
2012-09-19 Added RELATION is a GO:0097159 (organic cyclic compound binding)
2012-09-19 Added RELATION is a GO:0043169 (cation binding)
2012-09-19 Added RELATION is a GO:0043168 (anion binding)
2010-12-16 Added DEFINITION Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2010-12-16 Updated TERM thiamine pyrophosphate binding
2010-12-16 Deleted DEFINITION Interacting selectively and non-covalently with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2010-12-16 Deleted SYNONYM thiamine pyrophosphate binding
2010-12-16 Added SYNONYM thiamin pyrophosphate binding
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2009-07-03 Deleted DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2008-05-13 Added DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2008-05-12 Deleted DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2008-04-01 Updated RELATION is a GO:0019842 (vitamin binding)
2008-04-01 Updated RELATION is a GO:0050662 (coenzyme binding)
2007-08-09 Added SYNONYM TPP binding
2007-08-09 Added SYNONYM aneurine pyrophosphate binding
2007-08-09 Added SYNONYM cocarboxylase binding
2007-08-09 Added SYNONYM diphosphothiamin binding
2007-08-09 Added SYNONYM thiamine pyrophosphate binding
2007-08-09 Deleted SYNONYM TPP binding
2007-08-09 Deleted SYNONYM aneurine pyrophosphate binding
2007-08-09 Deleted SYNONYM cocarboxylase binding
2007-08-09 Deleted SYNONYM diphosphothiamin binding
2007-08-09 Deleted SYNONYM thiamine pyrophosphate binding
2004-10-29 Deleted SYNONYM thiamin pyrophosphate binding
2004-10-29 Added SYNONYM aneurine pyrophosphate binding
2004-10-29 Added SYNONYM cocarboxylase binding
2004-10-29 Added SYNONYM diphosphothiamin binding
2004-10-29 Added SYNONYM thiamine pyrophosphate binding
2004-10-28 Updated DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2004-10-08 Added SYNONYM TPP binding
2004-09-03 Added TERM thiamin pyrophosphate binding
2004-09-03 Added SYNONYM thiamin pyrophosphate binding
2004-09-03 Added DEFINITION Interacting selectively with thiamine pyrophosphate.

Term

Timestamp Action Category Detail
2010-12-16 Updated TERM thiamine pyrophosphate binding
2004-09-03 Added TERM thiamin pyrophosphate binding

Definition/synonyms

Timestamp Action Category Detail
2010-12-16 Added DEFINITION Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2010-12-16 Deleted DEFINITION Interacting selectively and non-covalently with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2010-12-16 Deleted SYNONYM thiamine pyrophosphate binding
2010-12-16 Added SYNONYM thiamin pyrophosphate binding
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2009-07-03 Deleted DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2008-05-13 Added DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2008-05-12 Deleted DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2007-08-09 Added SYNONYM TPP binding
2007-08-09 Added SYNONYM aneurine pyrophosphate binding
2007-08-09 Added SYNONYM cocarboxylase binding
2007-08-09 Added SYNONYM diphosphothiamin binding
2007-08-09 Added SYNONYM thiamine pyrophosphate binding
2007-08-09 Deleted SYNONYM TPP binding
2007-08-09 Deleted SYNONYM aneurine pyrophosphate binding
2007-08-09 Deleted SYNONYM cocarboxylase binding
2007-08-09 Deleted SYNONYM diphosphothiamin binding
2007-08-09 Deleted SYNONYM thiamine pyrophosphate binding
2004-10-29 Deleted SYNONYM thiamin pyrophosphate binding
2004-10-29 Added SYNONYM aneurine pyrophosphate binding
2004-10-29 Added SYNONYM cocarboxylase binding
2004-10-29 Added SYNONYM diphosphothiamin binding
2004-10-29 Added SYNONYM thiamine pyrophosphate binding
2004-10-28 Updated DEFINITION Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
2004-10-08 Added SYNONYM TPP binding
2004-09-03 Added SYNONYM thiamin pyrophosphate binding
2004-09-03 Added DEFINITION Interacting selectively with thiamine pyrophosphate.

Relationships

Timestamp Action Category Detail
2012-12-05 Added RELATION is a GO:1901681 (sulfur compound binding)
2012-09-19 Added RELATION is a GO:1901363 (heterocyclic compound binding)
2012-09-19 Added RELATION is a GO:0097159 (organic cyclic compound binding)
2012-09-19 Added RELATION is a GO:0043169 (cation binding)
2012-09-19 Added RELATION is a GO:0043168 (anion binding)
2008-04-01 Updated RELATION is a GO:0019842 (vitamin binding)
2008-04-01 Updated RELATION is a GO:0050662 (coenzyme binding)
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