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GO:0030968 endoplasmic reticulum unfolded protein response

The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.

Term Information

ID GO:0030968
Name endoplasmic reticulum unfolded protein response
Ontology Biological Process
Definition The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.
Comment Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any cellular response to the presence of unfolded proteins anywhere in the cell. Also see 'ER-associated protein catabolic process ; GO:0030433'.

Synonyms

Type Synonym
related SREBP-mediated signalling pathway
exact erUPR
exact ER unfolded protein response

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0050896 response to stimulus
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0006950 response to stress
GO:0009607 response to biotic stimulus
GO:0050789 regulation of biological process
GO:0042221 response to chemical stimulus
GO:0007154 cell communication
GO:0010033 response to organic substance
GO:0051716 cellular response to stimulus
GO:0051789 response to protein stimulus
GO:0050794 regulation of cellular process
GO:0070887 cellular response to chemical stimulus
GO:0033554 cellular response to stress
GO:0034976 response to endoplasmic reticulum stress
GO:0007165 signal transduction
GO:0007242 intracellular signaling cascade
GO:0006986 response to unfolded protein
GO:0006984 ER-nuclear signaling pathway
GO:0034620 cellular response to unfolded protein
GO:0030968 endoplasmic reticulum unfolded protein response

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0006987 activation of signaling protein activity involved in unfolded protein response
P GO:0006990 positive regulation of gene-specific transcription involved in unfolded protein response
P GO:0030969 UFP-specific transcription factor mRNA processing during unfolded protein response

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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