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GO:0030674 protein binding, bridging

Term Information

ID GO:0030674
Name protein binding, bridging
Ontology Molecular Function
Definition The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GONUTS GO:0030674 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow protein-protein adaptor

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Binding term considerationsLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_generic149
goslim_yeast169

Cross-references

Database ID
InterPro IPR007131
InterPro IPR012290
InterPro IPR022768
InterPro IPR024703

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008077 Hsp70/Hsp90 organizing protein activity CONSIDER GO:0030674
GO:0008546 microtubule/chromatin interaction CONSIDER GO:0030674
GO:0015472 fimbrium-specific chaperone activity CONSIDER GO:0030674
GO:0030400 protease substrate recruitment factor activity CONSIDER GO:0030674
GO:0003780 actin cross-linking activity REPLACEDBY GO:0030674
GO:0030022 adhesive extracellular matrix constituent REPLACEDBY GO:0030674

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030674:
Relationship To GO:0030674 Child Term Child Term Name
Is a GO:0008269 JAK pathway signal transduction adaptor activity
Is a GO:0005091 guanyl-nucleotide exchange factor adaptor activity
Is a GO:0019895 kinesin-associated mitochondrial adaptor activity
Is a GO:0017107 anion exchanger adaptor activity
Is a GO:0008093 cytoskeletal adaptor activity
Is a GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
Is a GO:0035615 clathrin adaptor activity
Is a GO:0005070 SH3/SH2 adaptor activity
Is a GO:0097020 COPII adaptor activity
Is a GO:0035656 kinesin-associated melanosomal adaptor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030674. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030674 based on the entire annotation set Co-occurrence statistics for GO:0030674 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_generic
2012-10-29 Added DEFINITION The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
2012-10-29 Deleted DEFINITION The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, permitting those molecules to function in a coordinated way.
2012-02-10 Added SLIM goslim_generic
2011-08-21 Deleted RELATION has part GO:0000988 (protein binding transcription factor activity)
2011-08-14 Added SLIM goslim_yeast
2011-06-05 Added RELATION has part GO:0000988 (protein binding transcription factor activity)
2010-12-03 Added RELATION is a GO:0060090 (binding, bridging)
2010-12-03 Deleted SYNONYM protein-protein adaptor
2010-12-03 Added SYNONYM protein-protein adaptor
2010-12-03 Deleted DEFINITION Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2010-12-03 Added DEFINITION The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, permitting those molecules to function in a coordinated way.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2009-07-03 Deleted DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2008-05-13 Added DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2008-05-12 Deleted DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
2007-08-09 Added SYNONYM protein-protein adaptor
2007-08-09 Deleted SYNONYM protein-protein adaptor
2006-02-09 Deleted SYNONYM Hsp70/Hsp90 organizing protein activity
2006-02-09 Deleted SYNONYM actin cross-linking activity
2006-02-09 Deleted SYNONYM adhesive extracellular matrix constituent
2006-02-09 Deleted SYNONYM fimbrium-specific chaperone activity
2006-02-09 Deleted SYNONYM microtubule/chromatin interaction
2006-02-09 Deleted SYNONYM protease substrate recruitment factor activity
2005-08-10 Added SYNONYM protease substrate recruitment factor activity
2005-08-10 Added SYNONYM Hsp70/Hsp90 organizing protein activity
2005-08-10 Added SYNONYM actin cross-linking activity
2005-08-10 Added SYNONYM adhesive extracellular matrix constituent
2005-08-10 Added SYNONYM fimbrium-specific chaperone activity
2005-08-10 Added SYNONYM microtubule/chromatin interaction
2005-03-19 Updated DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2003-06-10 Updated TERM protein binding, bridging
2003-04-23 Updated TERM protein binding activity, bridging
2003-04-23 Updated DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex simultaneously, thereby physically linking the bound proteins or complexes to each other.
2003-04-18 Added SYNONYM protein-protein adaptor
2003-04-18 Added TERM protein binding, bridging
2003-04-18 Added DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromelecule or complex simultaneously, thereby physically linking the bound proteins or complexes to each other.

Term

Timestamp Action Category Detail
2003-06-10 Updated TERM protein binding, bridging
2003-04-23 Updated TERM protein binding activity, bridging
2003-04-18 Added TERM protein binding, bridging

Definition/synonyms

Timestamp Action Category Detail
2012-10-29 Added DEFINITION The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
2012-10-29 Deleted DEFINITION The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, permitting those molecules to function in a coordinated way.
2010-12-03 Deleted SYNONYM protein-protein adaptor
2010-12-03 Added SYNONYM protein-protein adaptor
2010-12-03 Deleted DEFINITION Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2010-12-03 Added DEFINITION The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, permitting those molecules to function in a coordinated way.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2009-07-03 Deleted DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2008-05-13 Added DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2008-05-12 Deleted DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2007-08-09 Added SYNONYM protein-protein adaptor
2007-08-09 Deleted SYNONYM protein-protein adaptor
2006-02-09 Deleted SYNONYM Hsp70/Hsp90 organizing protein activity
2006-02-09 Deleted SYNONYM actin cross-linking activity
2006-02-09 Deleted SYNONYM adhesive extracellular matrix constituent
2006-02-09 Deleted SYNONYM fimbrium-specific chaperone activity
2006-02-09 Deleted SYNONYM microtubule/chromatin interaction
2006-02-09 Deleted SYNONYM protease substrate recruitment factor activity
2005-08-10 Added SYNONYM protease substrate recruitment factor activity
2005-08-10 Added SYNONYM Hsp70/Hsp90 organizing protein activity
2005-08-10 Added SYNONYM actin cross-linking activity
2005-08-10 Added SYNONYM adhesive extracellular matrix constituent
2005-08-10 Added SYNONYM fimbrium-specific chaperone activity
2005-08-10 Added SYNONYM microtubule/chromatin interaction
2005-03-19 Updated DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
2003-04-23 Updated DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex simultaneously, thereby physically linking the bound proteins or complexes to each other.
2003-04-18 Added SYNONYM protein-protein adaptor
2003-04-18 Added DEFINITION Interacting selectively with two or more protein molecules, or a protein and another macromelecule or complex simultaneously, thereby physically linking the bound proteins or complexes to each other.

Relationships

Timestamp Action Category Detail
2011-08-21 Deleted RELATION has part GO:0000988 (protein binding transcription factor activity)
2011-06-05 Added RELATION has part GO:0000988 (protein binding transcription factor activity)
2010-12-03 Added RELATION is a GO:0060090 (binding, bridging)
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_generic
2012-02-10 Added SLIM goslim_generic
2011-08-14 Added SLIM goslim_yeast
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