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GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activityCatalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
Term Information
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| Type | Synonym |
| exact | DXP-reductoisomerase activity |
| exact | 1-deoxyxylulose-5-phosphate reductoisomerase activity |
| exact | 2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity |
| exact | DOXP reductoisomerase activity |
| exact | 1-deoxy-D-xylulose-5-phosphate isomeroreductase activity |
| exact | 2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing) |
| Database | ID |
| INTERPRO | IPR013512 |
| INTERPRO | IPR003821 |
| EC | 1.1.1.267 |
| INTERPRO | IPR013644 |
| MetaCyc | DXPREDISOM-RXN |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016491 oxidoreductase activity | |||
![]() | ![]() | ![]() | GO:0016614 oxidoreductase activity, acting on CH-OH group of donors | ||
![]() | ![]() | ![]() | ![]() | GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |