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GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity

Term Information

ID GO:0030604
Name 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.
GONUTS GO:0030604 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact 2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)
exact 1-deoxy-D-xylulose-5-phosphate isomeroreductase activity
exact DXP-reductoisomerase activity
exact 1-deoxyxylulose-5-phosphate reductoisomerase activity
exact DOXP reductoisomerase activity
exact 2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.1.1.267
InterPro IPR003821
KEGG R05688
MetaCyc DXPREDISOM-RXN
RHEA 13720

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030604:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030604. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030604 based on the entire annotation set Co-occurrence statistics for GO:0030604 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.
2010-10-11 Added XREF KEGG:R05688
2010-10-11 Added XREF RHEA:13720
2008-05-13 Added DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2007-11-08 Added SYNONYM 1-deoxy-D-xylulose-5-phosphate isomeroreductase activity
2007-11-08 Added SYNONYM 2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)
2007-11-08 Added SYNONYM 2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity
2007-09-06 Added SYNONYM 1-deoxyxylulose-5-phosphate reductoisomerase activity
2007-09-06 Added SYNONYM DXP-reductoisomerase activity
2007-09-06 Deleted SYNONYM DXP-reductoisomerase
2007-08-09 Added SYNONYM DOXP reductoisomerase activity
2007-08-09 Added SYNONYM DXP-reductoisomerase
2007-08-09 Deleted SYNONYM DOXP reductoisomerase activity
2007-08-09 Deleted SYNONYM DXP-reductoisomerase
2007-01-22 Added SYNONYM DOXP reductoisomerase activity
2004-04-19 Added SYNONYM DXP-reductoisomerase
2004-04-16 Deleted SYNONYM DXP-reductoisomerase
2003-10-27 Added SYNONYM DXP-reductoisomerase
2003-10-27 Added XREF MetaCyc:DXPREDISOM-RXN
2003-08-21 Deleted SYNONYM DXP-reductoisomerase
2003-03-19 Updated TERM 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2002-04-08 Added TERM 1-deoxy-D-xylulose-5-phosphate reductoisomerase
2002-04-08 Added SYNONYM DXP-reductoisomerase
2002-04-08 Added XREF EC:1.1.1.267

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
2002-04-08 Added TERM 1-deoxy-D-xylulose-5-phosphate reductoisomerase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2007-11-08 Added SYNONYM 1-deoxy-D-xylulose-5-phosphate isomeroreductase activity
2007-11-08 Added SYNONYM 2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)
2007-11-08 Added SYNONYM 2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity
2007-09-06 Added SYNONYM 1-deoxyxylulose-5-phosphate reductoisomerase activity
2007-09-06 Added SYNONYM DXP-reductoisomerase activity
2007-09-06 Deleted SYNONYM DXP-reductoisomerase
2007-08-09 Added SYNONYM DOXP reductoisomerase activity
2007-08-09 Added SYNONYM DXP-reductoisomerase
2007-08-09 Deleted SYNONYM DOXP reductoisomerase activity
2007-08-09 Deleted SYNONYM DXP-reductoisomerase
2007-01-22 Added SYNONYM DOXP reductoisomerase activity
2004-04-19 Added SYNONYM DXP-reductoisomerase
2004-04-16 Deleted SYNONYM DXP-reductoisomerase
2003-10-27 Added SYNONYM DXP-reductoisomerase
2003-08-21 Deleted SYNONYM DXP-reductoisomerase
2002-11-27 Added DEFINITION Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
2002-04-08 Added SYNONYM DXP-reductoisomerase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF KEGG:R05688
2010-10-11 Added XREF RHEA:13720
2003-10-27 Added XREF MetaCyc:DXPREDISOM-RXN
2002-04-08 Added XREF EC:1.1.1.267
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