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GO:0030330 DNA damage response, signal transduction by p53 class mediator

Term Information

ID GO:0030330
Name DNA damage response, signal transduction by p53 class mediator
Ontology Biological Process
Definition A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Secondary IDs GO:0006976
GONUTS GO:0030330 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related TP53 signaling pathway
related p53 signaling pathway
broad p53-mediated DNA damage response
related DNA damage response, activation of p53

GO Discussions

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Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR028767

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030330:
Relationship To GO:0030330 Child Term Child Term Name
Is a GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Is a GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Regulates GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator
Positively regulates GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
Negatively regulates GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030330. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030330 based on the entire annotation set Co-occurrence statistics for GO:0030330 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-05-06 Added RELATION is a GO:0072331 (signal transduction by p53 class mediator)
2009-11-24 Added SYNONYM TP53 signaling pathway
2009-11-24 Added SYNONYM p53 signaling pathway
2008-05-13 Added DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2008-05-12 Deleted DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2008-04-01 Updated RELATION is a GO:0042770 (signal transduction in response to DNA damage)
2007-08-09 Added SYNONYM DNA damage response, activation of p53
2007-08-09 Added SYNONYM p53-mediated DNA damage response
2007-08-09 Deleted SYNONYM DNA damage response, activation of p53
2007-08-09 Deleted SYNONYM p53-mediated DNA damage response
2005-10-14 Updated DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2004-04-19 Added SYNONYM DNA damage response, activation of p53
2004-04-19 Added SYNONYM p53-mediated DNA damage response
2004-04-16 Deleted SYNONYM p53-mediated DNA damage response
2004-04-05 Deleted SYNONYM DNA damage response, activation of p53
2003-06-21 Added SECONDARY GO:0006976 (DNA damage response, activation of p53)
2003-06-21 Added SYNONYM DNA damage response, activation of p53
2003-06-21 Added SYNONYM p53-mediated DNA damage response
2003-06-21 Updated TERM DNA damage response, signal transduction by p53 class mediator
2003-06-21 Added DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the perception of DNA damage.
2001-10-04 Added TERM p53-mediated DNA damage response

Term

Timestamp Action Category Detail
2003-06-21 Updated TERM DNA damage response, signal transduction by p53 class mediator
2001-10-04 Added TERM p53-mediated DNA damage response

Definition/synonyms

Timestamp Action Category Detail
2009-11-24 Added SYNONYM TP53 signaling pathway
2009-11-24 Added SYNONYM p53 signaling pathway
2008-05-13 Added DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2008-05-12 Deleted DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2007-08-09 Added SYNONYM DNA damage response, activation of p53
2007-08-09 Added SYNONYM p53-mediated DNA damage response
2007-08-09 Deleted SYNONYM DNA damage response, activation of p53
2007-08-09 Deleted SYNONYM p53-mediated DNA damage response
2005-10-14 Updated DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2004-04-19 Added SYNONYM DNA damage response, activation of p53
2004-04-19 Added SYNONYM p53-mediated DNA damage response
2004-04-16 Deleted SYNONYM p53-mediated DNA damage response
2004-04-05 Deleted SYNONYM DNA damage response, activation of p53
2003-06-21 Added SYNONYM DNA damage response, activation of p53
2003-06-21 Added SYNONYM p53-mediated DNA damage response
2003-06-21 Added DEFINITION A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the perception of DNA damage.

Relationships

Timestamp Action Category Detail
2011-05-06 Added RELATION is a GO:0072331 (signal transduction by p53 class mediator)
2008-04-01 Updated RELATION is a GO:0042770 (signal transduction in response to DNA damage)

Other

Timestamp Action Category Detail
2003-06-21 Added SECONDARY GO:0006976 (DNA damage response, activation of p53)
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