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GO:0030324 lung development

The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.

Term Information

ID GO:0030324
Name lung development
Ontology Biological Process
Definition The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
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Ancestor Table

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GO:0008150 biological_process
GO:0032501 multicellular organismal process
GO:0032502 developmental process
GO:0048856 anatomical structure development
GO:0007275 multicellular organismal development
GO:0035295 tube development
GO:0048731 system development
GO:0060541 respiratory system development
GO:0048513 organ development
GO:0030323 respiratory tube development
GO:0030324 lung development

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0048286 lung alveolus development
P GO:0060425 lung morphogenesis
P GO:0060426 lung vasculature development
P GO:0060427 lung connective tissue development
P GO:0060428 lung epithelium development
P GO:0060430 lung saccule development
P GO:0060432 lung pattern specification process
P GO:0060435 bronchiole development
P GO:0060437 lung growth
P GO:0060479 lung cell differentiation
P GO:0060484 lung-associated mesenchyme development
P GO:0060495 cell-cell signaling involved in lung development
P GO:0060915 mesenchymal cell differentiation involved in lung development
P GO:0060916 mesenchymal cell proliferation involved in lung development
I GO:0060458 right lung development
I GO:0060459 left lung development
P GO:0060462 lung lobe development

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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12ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-21-04-03-45
Terminal
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