spacer

GO:0030217 T cell differentiation

Term Information

ID GO:0030217
Name T cell differentiation
Ontology Biological Process
Definition The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
Comment This term was improved by GO_REF:0000022. It was moved. Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Secondary IDs GO:0042112 GO:0046652
GONUTS GO:0030217 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact T-cell differentiation
exact T lymphocyte differentiation
exact T-lymphocyte differentiation
related T cell development

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0002376 immune system process never_in_taxon 4895 Schizosaccharomyces
GO:0007159 leukocyte cell-cell adhesion never_in_taxon 33090 Viridiplantae
GO:0007159 leukocyte cell-cell adhesion never_in_taxon 2, 2157, 4751 Fungi or Bacteria or Archaea
GO:0032501 multicellular organismal process never_in_taxon 4896 Schizosaccharomyces pombe
GO:0032501 multicellular organismal process never_in_taxon 4932 Saccharomyces cerevisiae
GO:0032501 multicellular organismal process only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000084 T cell

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030217:
Relationship To GO:0030217 Child Term Child Term Name
Is a GO:0045065 cytotoxic T cell differentiation
Is a GO:0045066 regulatory T cell differentiation
Is a GO:0042492 gamma-delta T cell differentiation
Is a GO:0046632 alpha-beta T cell differentiation
Part of GO:0002568 somatic diversification of T cell receptor genes
Part of GO:0002572 pro-T cell differentiation
Regulates GO:0045580 regulation of T cell differentiation
Negatively regulates GO:0045581 negative regulation of T cell differentiation
Positively regulates GO:0045582 positive regulation of T cell differentiation
Is a GO:0033077 T cell differentiation in thymus
Is a GO:0033078 extrathymic T cell differentiation
Is a GO:0002292 T cell differentiation involved in immune response
Part of GO:0002360 T cell lineage commitment
Part of GO:0045058 T cell selection

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030217. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030217 based on the entire annotation set Co-occurrence statistics for GO:0030217 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-12-01 Deleted DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2010-12-01 Added DEFINITION The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2010-10-15 Added SYNONYM T cell development
2010-10-14 Deleted SYNONYM T cell development
2010-10-14 Deleted SYNONYM T-cell development
2008-05-13 Added DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2008-05-12 Deleted DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2008-04-01 Updated RELATION is a GO:0042110 (T cell activation)
2008-04-01 Updated RELATION is a GO:0030098 (lymphocyte differentiation)
2008-03-11 Updated DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2007-10-07 Added SYNONYM T-cell development
2007-10-07 Deleted SYNONYM T cell differentiation
2007-08-09 Added SYNONYM T cell development
2007-08-09 Added SYNONYM T cell differentiation
2007-08-09 Added SYNONYM T lymphocyte differentiation
2007-08-09 Added SYNONYM T-cell differentiation
2007-08-09 Added SYNONYM T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM T cell development
2007-08-09 Deleted SYNONYM T cell differentiation
2007-08-09 Deleted SYNONYM T lymphocyte differentiation
2007-08-09 Deleted SYNONYM T-cell differentiation
2007-08-09 Deleted SYNONYM T-lymphocyte differentiation
2007-03-30 Deleted SYNONYM thymocyte cell differentiation
2007-03-30 Deleted SYNONYM thymocyte differentiation
2005-06-02 Added SYNONYM T lymphocyte differentiation
2005-06-02 Added SYNONYM T-cell differentiation
2005-06-02 Added SYNONYM T-lymphocyte differentiation
2005-06-02 Deleted SYNONYM T-cell development
2005-06-02 Updated DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a T cell.
2005-06-02 Updated TERM T cell differentiation
2005-05-26 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a T cell.
2005-05-23 Added SYNONYM T cell development
2005-05-23 Added SYNONYM T-cell development
2005-05-23 Added SYNONYM thymocyte cell differentiation
2005-05-23 Added SYNONYM thymocyte differentiation
2005-05-23 Added SECONDARY GO:0046652 (thymocyte differentiation)
2005-01-21 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a T-cell.
2004-04-19 Added SYNONYM T cell differentiation
2004-04-16 Deleted SYNONYM T cell differentiation
2004-02-11 Added SYNONYM T cell differentiation
2002-11-27 Added DEFINITION The process by which a hemopoietic stem cell acquires characteristics of a T-cell.
2002-02-19 Updated TERM T-cell differentiation
2001-09-05 Added TERM T cell differentiation

Term

Timestamp Action Category Detail
2005-06-02 Updated TERM T cell differentiation
2002-02-19 Updated TERM T-cell differentiation
2001-09-05 Added TERM T cell differentiation

Definition/synonyms

Timestamp Action Category Detail
2010-12-01 Deleted DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2010-12-01 Added DEFINITION The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2010-10-15 Added SYNONYM T cell development
2010-10-14 Deleted SYNONYM T cell development
2010-10-14 Deleted SYNONYM T-cell development
2008-05-13 Added DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2008-05-12 Deleted DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2008-03-11 Updated DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2007-10-07 Added SYNONYM T-cell development
2007-10-07 Deleted SYNONYM T cell differentiation
2007-08-09 Added SYNONYM T cell development
2007-08-09 Added SYNONYM T cell differentiation
2007-08-09 Added SYNONYM T lymphocyte differentiation
2007-08-09 Added SYNONYM T-cell differentiation
2007-08-09 Added SYNONYM T-lymphocyte differentiation
2007-08-09 Deleted SYNONYM T cell development
2007-08-09 Deleted SYNONYM T cell differentiation
2007-08-09 Deleted SYNONYM T lymphocyte differentiation
2007-08-09 Deleted SYNONYM T-cell differentiation
2007-08-09 Deleted SYNONYM T-lymphocyte differentiation
2007-03-30 Deleted SYNONYM thymocyte cell differentiation
2007-03-30 Deleted SYNONYM thymocyte differentiation
2005-06-02 Added SYNONYM T lymphocyte differentiation
2005-06-02 Added SYNONYM T-cell differentiation
2005-06-02 Added SYNONYM T-lymphocyte differentiation
2005-06-02 Deleted SYNONYM T-cell development
2005-06-02 Updated DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a T cell.
2005-05-26 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a T cell.
2005-05-23 Added SYNONYM T cell development
2005-05-23 Added SYNONYM T-cell development
2005-05-23 Added SYNONYM thymocyte cell differentiation
2005-05-23 Added SYNONYM thymocyte differentiation
2005-01-21 Updated DEFINITION Processes whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a T-cell.
2004-04-19 Added SYNONYM T cell differentiation
2004-04-16 Deleted SYNONYM T cell differentiation
2004-02-11 Added SYNONYM T cell differentiation
2002-11-27 Added DEFINITION The process by which a hemopoietic stem cell acquires characteristics of a T-cell.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0042110 (T cell activation)
2008-04-01 Updated RELATION is a GO:0030098 (lymphocyte differentiation)

Other

Timestamp Action Category Detail
2005-05-23 Added SECONDARY GO:0046652 (thymocyte differentiation)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
998ms