spacer

GO:0030178 negative regulation of Wnt signaling pathway

Term Information

ID GO:0030178
Name negative regulation of Wnt signaling pathway
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
Secondary IDs GO:0045810
GONUTS GO:0030178 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact downregulation of Wnt receptor signaling pathway
narrow inhibition of Wnt receptor signaling pathway
exact negative regulation of Wnt receptor signalling pathway
exact down regulation of Wnt receptor signaling pathway
exact down-regulation of Wnt receptor signaling pathway
exact down regulation of frizzled signaling pathway
exact negative regulation of Wnt receptor signaling pathway
exact downregulation of frizzled signaling pathway
narrow inhibition of frizzled signaling pathway
exact negative regulation of frizzled signaling pathway
exact negative regulation of frizzled signalling pathway
exact negative regulation of Wnt-activated signaling pathway
exact down-regulation of frizzled signaling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR006796
InterPro IPR026818
InterPro IPR026836

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030178:
Relationship To GO:0030178 Child Term Child Term Name
Is a GO:0003308 negative regulation of Wnt signaling pathway involved in heart development
Is a GO:2000051 negative regulation of non-canonical Wnt signaling pathway
Is a GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
Is a GO:2000057 negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis
Is a GO:0090090 negative regulation of canonical Wnt signaling pathway
Is a GO:0038012 negative regulation of Wnt signaling pathway by Wnt receptor internalization
Part of GO:0038018 Wnt receptor catabolic process

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030178. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030178 based on the entire annotation set Co-occurrence statistics for GO:0030178 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-11 Updated TERM negative regulation of Wnt signaling pathway
2013-12-11 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2013-12-11 Added SYNONYM negative regulation of Wnt receptor signaling pathway
2013-12-11 Added SYNONYM negative regulation of Wnt-activated signaling pathway
2013-12-11 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
2011-01-16 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2011-01-16 Deleted RELATION is a GO:0035467 (negative regulation of signaling pathway)
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2010-04-21 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2010-04-21 Added RELATION is a GO:0035467 (negative regulation of signaling pathway)
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2008-04-01 Updated RELATION is a GO:0030111 (regulation of Wnt signaling pathway)
2008-04-01 Added RELATION negatively regulates GO:0016055 (Wnt signaling pathway)
2008-04-01 Updated RELATION is a GO:0009968 (negative regulation of signal transduction)
2007-11-08 Added SYNONYM down regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM down-regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM downregulation of frizzled signaling pathway
2007-11-08 Added SYNONYM inhibition of frizzled signaling pathway
2007-11-08 Added SYNONYM negative regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM negative regulation of frizzled signalling pathway
2007-11-08 Added SECONDARY GO:0045810 (negative regulation of frizzled signaling pathway)
2007-08-09 Added SYNONYM down regulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM down-regulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM downregulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM inhibition of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM negative regulation of Wnt receptor signalling pathway
2007-08-09 Deleted SYNONYM down regulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM down-regulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM downregulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM inhibition of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of Wnt receptor signalling pathway
2007-02-23 Added SYNONYM down regulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM down-regulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM downregulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM inhibition of Wnt receptor signaling pathway
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Wnt receptor signaling pathway activity.
2004-04-19 Added SYNONYM negative regulation of Wnt receptor signalling pathway
2004-04-16 Deleted SYNONYM negative regulation of Wnt receptor signalling pathway
2003-11-13 Added SYNONYM negative regulation of Wnt receptor signalling pathway
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of Wnt receptor signaling pathway activity.
2002-07-15 Updated TERM negative regulation of Wnt receptor signaling pathway
2001-08-30 Added TERM inhibition of Wnt receptor signaling pathway

Term

Timestamp Action Category Detail
2013-12-11 Updated TERM negative regulation of Wnt signaling pathway
2002-07-15 Updated TERM negative regulation of Wnt receptor signaling pathway
2001-08-30 Added TERM inhibition of Wnt receptor signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2013-12-11 Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2013-12-11 Added SYNONYM negative regulation of Wnt receptor signaling pathway
2013-12-11 Added SYNONYM negative regulation of Wnt-activated signaling pathway
2013-12-11 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2007-11-08 Added SYNONYM down regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM down-regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM downregulation of frizzled signaling pathway
2007-11-08 Added SYNONYM inhibition of frizzled signaling pathway
2007-11-08 Added SYNONYM negative regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM negative regulation of frizzled signalling pathway
2007-08-09 Added SYNONYM down regulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM down-regulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM downregulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM inhibition of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM negative regulation of Wnt receptor signalling pathway
2007-08-09 Deleted SYNONYM down regulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM down-regulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM downregulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM inhibition of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM negative regulation of Wnt receptor signalling pathway
2007-02-23 Added SYNONYM down regulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM down-regulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM downregulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM inhibition of Wnt receptor signaling pathway
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Wnt receptor signaling pathway activity.
2004-04-19 Added SYNONYM negative regulation of Wnt receptor signalling pathway
2004-04-16 Deleted SYNONYM negative regulation of Wnt receptor signalling pathway
2003-11-13 Added SYNONYM negative regulation of Wnt receptor signalling pathway
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of Wnt receptor signaling pathway activity.

Relationships

Timestamp Action Category Detail
2011-01-16 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2011-01-16 Deleted RELATION is a GO:0035467 (negative regulation of signaling pathway)
2010-04-21 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2010-04-21 Added RELATION is a GO:0035467 (negative regulation of signaling pathway)
2008-04-01 Updated RELATION is a GO:0030111 (regulation of Wnt signaling pathway)
2008-04-01 Added RELATION negatively regulates GO:0016055 (Wnt signaling pathway)
2008-04-01 Updated RELATION is a GO:0009968 (negative regulation of signal transduction)

Other

Timestamp Action Category Detail
2007-11-08 Added SECONDARY GO:0045810 (negative regulation of frizzled signaling pathway)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
17ms