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GO:0030176 integral component of endoplasmic reticulum membrane

Term Information

ID GO:0030176
Name integral component of endoplasmic reticulum membrane
Ontology Cellular Component
Definition The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
GONUTS GO:0030176 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact ER integral membrane protein
exact integral to ER membrane
narrow integral to endoplasmic reticulum membrane

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000063 GO:0005783 endoplasmic reticulum only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR007794
InterPro IPR009703
InterPro IPR009779
InterPro IPR009914
InterPro IPR009952
InterPro IPR011553
InterPro IPR026566

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030176:
Relationship To GO:0030176 Child Term Child Term Name
Part of GO:0042765 GPI-anchor transamidase complex
Part of GO:0032937 SREBP-SCAP-Insig complex
Part of GO:0042824 MHC class I peptide loading complex
Is a GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
Is a GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
Part of GO:0072546 ER membrane protein complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
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Name
Synonym
Type
Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030176. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030176 based on the entire annotation set Co-occurrence statistics for GO:0030176 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-01-16 Added RELATION is a GO:0044432 (endoplasmic reticulum part)
2013-12-21 Updated TERM integral component of endoplasmic reticulum membrane
2013-12-21 Deleted DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Added DEFINITION The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Added SYNONYM integral to endoplasmic reticulum membrane
2013-12-21 Added RELATION part of GO:0031227 (intrinsic component of endoplasmic reticulum membrane)
2013-12-21 Deleted RELATION is a GO:0031227 (intrinsic component of endoplasmic reticulum membrane)
2008-05-13 Added DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2008-05-12 Deleted DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2008-04-01 Updated RELATION is a GO:0031301 (integral component of organelle membrane)
2008-04-01 Updated RELATION is a GO:0031227 (intrinsic component of endoplasmic reticulum membrane)
2007-08-09 Added SYNONYM ER integral membrane protein
2007-08-09 Added SYNONYM integral to ER membrane
2007-08-09 Deleted SYNONYM ER integral membrane protein
2007-08-09 Deleted SYNONYM integral to ER membrane
2005-11-12 Updated DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2004-11-09 Added SYNONYM integral to ER membrane
2004-04-19 Added SYNONYM ER integral membrane protein
2004-04-16 Deleted SYNONYM ER integral membrane protein
2003-09-13 Updated DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.
2003-06-19 Updated TERM integral to endoplasmic reticulum membrane
2002-11-27 Added DEFINITION An integral membrane protein found in membranes of the endoplasmic reticulum.
2002-07-26 Updated TERM endoplasmic reticulum membrane, intrinsic protein
2001-08-30 Added SYNONYM ER integral membrane protein
2001-08-30 Added TERM endoplasmic reticulum membrane, integral protein

Term

Timestamp Action Category Detail
2013-12-21 Updated TERM integral component of endoplasmic reticulum membrane
2003-06-19 Updated TERM integral to endoplasmic reticulum membrane
2002-07-26 Updated TERM endoplasmic reticulum membrane, intrinsic protein
2001-08-30 Added TERM endoplasmic reticulum membrane, integral protein

Definition/synonyms

Timestamp Action Category Detail
2013-12-21 Deleted DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Added DEFINITION The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
2013-12-21 Added SYNONYM integral to endoplasmic reticulum membrane
2008-05-13 Added DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2008-05-12 Deleted DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2007-08-09 Added SYNONYM ER integral membrane protein
2007-08-09 Added SYNONYM integral to ER membrane
2007-08-09 Deleted SYNONYM ER integral membrane protein
2007-08-09 Deleted SYNONYM integral to ER membrane
2005-11-12 Updated DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
2004-11-09 Added SYNONYM integral to ER membrane
2004-04-19 Added SYNONYM ER integral membrane protein
2004-04-16 Deleted SYNONYM ER integral membrane protein
2003-09-13 Updated DEFINITION Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.
2002-11-27 Added DEFINITION An integral membrane protein found in membranes of the endoplasmic reticulum.
2001-08-30 Added SYNONYM ER integral membrane protein

Relationships

Timestamp Action Category Detail
2014-01-16 Added RELATION is a GO:0044432 (endoplasmic reticulum part)
2013-12-21 Added RELATION part of GO:0031227 (intrinsic component of endoplasmic reticulum membrane)
2013-12-21 Deleted RELATION is a GO:0031227 (intrinsic component of endoplasmic reticulum membrane)
2008-04-01 Updated RELATION is a GO:0031301 (integral component of organelle membrane)
2008-04-01 Updated RELATION is a GO:0031227 (intrinsic component of endoplasmic reticulum membrane)
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