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GO:0030154 cell differentiation

Term Information

ID GO:0030154
Name cell differentiation
Ontology Biological Process
Definition The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GONUTS GO:0030154 Wiki Page

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_generic149
goslim_plant100

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000000 cell

Cross-references

Database ID
InterPro IPR000800
InterPro IPR009800
InterPro IPR010660
InterPro IPR011656
InterPro IPR026754
InterPro IPR028671
InterPro IPR029616
InterPro IPR029820
InterPro IPR029874
InterPro IPR030117
InterPro IPR030118
InterPro IPR030119
InterPro IPR030499
InterPro IPR030500
UniProtKB-KW Differentiation
Wikipedia Cellular_differentiation

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030154:
Relationship To GO:0030154 Child Term Child Term Name
Part of GO:0048468 cell development
Is a GO:0048824 pigment cell precursor differentiation
Is a GO:0060034 notochord cell differentiation
Is a GO:0001649 osteoblast differentiation
Is a GO:0030435 sporulation resulting in formation of a cellular spore
Is a GO:0014001 sclerenchyma cell differentiation
Is a GO:0042692 muscle cell differentiation
Is a GO:0061005 cell differentiation involved in kidney development
Is a GO:0009559 embryo sac central cell differentiation
Is a GO:0009560 embryo sac egg cell differentiation
Is a GO:0009563 synergid differentiation
Is a GO:0030182 neuron differentiation
Is a GO:0030855 epithelial cell differentiation
Is a GO:0030099 myeloid cell differentiation
Is a GO:0048759 xylem vessel member cell differentiation
Is a GO:0048760 plant parenchymal cell differentiation
Is a GO:0048761 collenchyma cell differentiation
Is a GO:0050931 pigment cell differentiation
Is a GO:0048235 pollen sperm cell differentiation
Is a GO:0042675 compound eye cone cell differentiation
Is a GO:0035051 cardiocyte differentiation
Is a GO:0042386 hemocyte differentiation
Is a GO:0045444 fat cell differentiation
Is a GO:0048657 anther wall tapetum cell differentiation
Is a GO:0048533 sporocyte differentiation
Is a GO:0002268 follicular dendritic cell differentiation
Is a GO:0001826 inner cell mass cell differentiation
Is a GO:0001829 trophectodermal cell differentiation
Is a GO:0002062 chondrocyte differentiation
Is a GO:0001570 vasculogenesis
Is a GO:0043158 heterocyst differentiation
Is a GO:0009557 antipodal cell differentiation
Is a GO:0002521 leukocyte differentiation
Is a GO:0009994 oocyte differentiation
Is a GO:0010001 glial cell differentiation
Part of GO:0045165 cell fate commitment
Is a GO:0061318 renal filtration cell differentiation
Is a GO:0001742 oenocyte differentiation
Regulates GO:0045595 regulation of cell differentiation
Negatively regulates GO:0045596 negative regulation of cell differentiation
Positively regulates GO:0045597 positive regulation of cell differentiation
Is a GO:0060126 somatotropin secreting cell differentiation
Is a GO:0060127 prolactin secreting cell differentiation
Is a GO:0060128 corticotropin hormone secreting cell differentiation
Is a GO:0008583 mystery cell differentiation
Is a GO:0010444 guard mother cell differentiation
Is a GO:0090104 pancreatic epsilon cell differentiation
Is a GO:0022036 rhombomere cell differentiation
Is a GO:0021515 cell differentiation in spinal cord
Is a GO:0021533 cell differentiation in hindbrain
Is a GO:0033327 Leydig cell differentiation
Is a GO:0060290 transdifferentiation
Is a GO:0061382 Malpighian tubule tip cell differentiation
Is a GO:0048888 neuromast mantle cell differentiation
Is a GO:0048889 neuromast support cell differentiation
Is a GO:0060479 lung cell differentiation
Is a GO:1903728 luteal cell differentiation
Is a GO:0022619 generative cell differentiation
Is a GO:0022620 vegetative cell differentiation
Is a GO:0090077 foam cell differentiation
Is a GO:0010480 microsporocyte differentiation
Is a GO:0048333 mesodermal cell differentiation
Is a GO:0075301 cell differentiation involved in spore germination
Is a GO:0022008 neurogenesis
Is a GO:0048863 stem cell differentiation
Part of GO:0070315 G1 to G0 transition involved in cell differentiation
Is a GO:0010668 ectodermal cell differentiation
Is a GO:0060591 chondroblast differentiation
Is a GO:0002244 hematopoietic progenitor cell differentiation
Is a GO:0060689 cell differentiation involved in salivary gland development
Is a GO:0060706 cell differentiation involved in embryonic placenta development
Is a GO:0021979 hypothalamus cell differentiation
Is a GO:0060718 chorionic trophoblast cell differentiation
Is a GO:0048515 spermatid differentiation
Is a GO:0090603 sieve element differentiation
Is a GO:0010026 trichome differentiation
Is a GO:0010052 guard cell differentiation
Is a GO:0010053 root epidermal cell differentiation
Is a GO:0090392 sepal giant cell differentiation
Is a GO:0090437 socket cell differentiation
Is a GO:1903498 bundle sheath cell differentiation
Is a GO:0035987 endodermal cell differentiation
Is a GO:0035990 tendon cell differentiation
Is a GO:0061521 hepatic stellate cell differentiation
Is a GO:0035914 skeletal muscle cell differentiation
Is a GO:0036446 myofibroblast differentiation
Is a GO:0044671 sorocarp spore cell differentiation

Protein Annotation

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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030154. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030154 based on the entire annotation set Co-occurrence statistics for GO:0030154 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_generic
2011-03-18 Deleted SLIM goslim_goa
2010-12-17 Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 Added DEFINITION The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-05-02 Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-05-02 Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2009-03-29 Added XREF Wikipedia:Cellular_differentiation
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
2008-05-13 Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2008-05-12 Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2008-04-01 Updated RELATION is a GO:0048869 (cellular developmental process)
2005-10-14 Updated DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2004-09-29 Updated TERM cell differentiation
2004-03-13 Updated DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
2003-10-18 Updated DEFINITION The process whereby relatively unspecialized cells, eg. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
2003-04-24 Updated DEFINITION The process whereby relatively unspecialized cells, e. g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
2002-11-27 Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
2001-08-22 Added TERM cell differentiation

Term

Timestamp Action Category Detail
2004-09-29 Updated TERM cell differentiation
2001-08-22 Added TERM cell differentiation

Definition/synonyms

Timestamp Action Category Detail
2010-12-17 Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 Added DEFINITION The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-05-02 Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-05-02 Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2008-05-13 Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2008-05-12 Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2005-10-14 Updated DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2004-03-13 Updated DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
2003-10-18 Updated DEFINITION The process whereby relatively unspecialized cells, eg. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
2003-04-24 Updated DEFINITION The process whereby relatively unspecialized cells, e. g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
2002-11-27 Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0048869 (cellular developmental process)

Cross-references

Timestamp Action Category Detail
2009-03-29 Added XREF Wikipedia:Cellular_differentiation

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_generic
2011-03-18 Deleted SLIM goslim_goa
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
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