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GO:0030150 protein import into mitochondrial matrix

The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.

Term Information

ID GO:0030150
Name protein import into mitochondrial matrix
Ontology Biological Process
Definition The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.
Comment

Synonyms

Type Synonym
exact mitochondrial matrix protein import
exact protein transport into mitochondrial matrix
broad mitochondrial translocation

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Ancestor Table

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GO:0008150 biological_process
GO:0051179 localization
GO:0009987 cellular process
GO:0016043 cellular component organization
GO:0051234 establishment of localization
GO:0033036 macromolecule localization
GO:0006810 transport
GO:0051641 cellular localization
GO:0006996 organelle organization
GO:0008104 protein localization
GO:0007005 mitochondrion organization
GO:0055085 transmembrane transport
GO:0070727 cellular macromolecule localization
GO:0051649 establishment of localization in cell
GO:0045184 establishment of protein localization
GO:0046907 intracellular transport
GO:0034613 cellular protein localization
GO:0015031 protein transport
GO:0017038 protein import
GO:0006839 mitochondrial transport
GO:0033365 protein localization in organelle
GO:0070585 protein localization in mitochondrion
GO:0006886 intracellular protein transport
GO:0006605 protein targeting
GO:0065002 intracellular protein transmembrane transport
GO:0006626 protein targeting to mitochondrion
GO:0030150 protein import into mitochondrial matrix

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
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Taxonomy
From
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Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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