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GO:0030141 secretory granule

Term Information

ID GO:0030141
Name secretory granule
Ontology Cellular Component
Definition A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
Comment Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'.
GONUTS GO:0030141 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad secretory vesicle

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000013 GO:0030141 secretory granule never_in_taxon 4890 Ascomycota
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR001819
InterPro IPR001990
InterPro IPR007945
InterPro IPR008836

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005803 secretory vesicle CONSIDER GO:0030141

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030141:
Relationship To GO:0030141 Child Term Child Term Name
Part of GO:0030667 secretory granule membrane
Is a GO:0042581 specific granule
Is a GO:0042582 azurophil granule
Is a GO:0042583 chromaffin granule
Is a GO:0042588 zymogen granule
Is a GO:0042827 platelet dense granule
Is a GO:0098594 mucin granule
Is a GO:0031045 dense core granule
Is a GO:0031091 platelet alpha granule
Is a GO:0042599 lamellar body
Is a GO:0032593 insulin-responsive compartment
Is a GO:0060473 cortical granule
Is a GO:0070820 tertiary granule
Is a GO:0033093 Weibel-Palade body
Part of GO:0034774 secretory granule lumen
Is a GO:0001669 acrosomal vesicle
Is a GO:0036000 mucocyst

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030141. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030141 based on the entire annotation set Co-occurrence statistics for GO:0030141 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-01-24 Added RELATION part of GO:0012505 (endomembrane system)
2011-11-26 Updated TERM secretory granule
2010-06-17 Updated TERM stored secretory granule
2010-06-17 Deleted DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2010-06-17 Added DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2008-05-13 Added DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2008-05-12 Deleted DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2008-04-01 Updated RELATION is a GO:0016023 (cytoplasmic membrane-bounded vesicle)
2007-08-09 Added SYNONYM secretory vesicle
2007-08-09 Deleted SYNONYM secretory vesicle
2007-07-27 Updated DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2002-11-27 Added DEFINITION A small subcellular vesicle, surrounded by a single-layered membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2001-08-21 Added SYNONYM secretory vesicle
2001-08-21 Added TERM secretory granule

Term

Timestamp Action Category Detail
2011-11-26 Updated TERM secretory granule
2010-06-17 Updated TERM stored secretory granule
2001-08-21 Added TERM secretory granule

Definition/synonyms

Timestamp Action Category Detail
2010-06-17 Deleted DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2010-06-17 Added DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2008-05-13 Added DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2008-05-12 Deleted DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2007-08-09 Added SYNONYM secretory vesicle
2007-08-09 Deleted SYNONYM secretory vesicle
2007-07-27 Updated DEFINITION A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2002-11-27 Added DEFINITION A small subcellular vesicle, surrounded by a single-layered membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2001-08-21 Added SYNONYM secretory vesicle

Relationships

Timestamp Action Category Detail
2014-01-24 Added RELATION part of GO:0012505 (endomembrane system)
2008-04-01 Updated RELATION is a GO:0016023 (cytoplasmic membrane-bounded vesicle)
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