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GO:0030123 AP-3 adaptor complex

Term Information

ID GO:0030123
Name AP-3 adaptor complex
Ontology Cellular Component
Definition A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
PMID:10611976 PMID:21097499
GONUTS GO:0030123 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR026740
InterPro IPR027155

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030123:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030123. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030123 based on the entire annotation set Co-occurrence statistics for GO:0030123 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-01-27 Added DEFINITION A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
2011-01-27 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2008-05-13 Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2008-05-12 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2008-04-01 Updated RELATION is a GO:0030119 (AP-type membrane coat adaptor complex)
2007-07-27 Updated DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2007-06-27 Updated DEFINITION A membrane coat adaptor complex found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2002-11-27 Added DEFINITION An adaptor complex found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2001-08-21 Added TERM AP-3 adaptor complex

Term

Timestamp Action Category Detail
2001-08-21 Added TERM AP-3 adaptor complex

Definition/synonyms

Timestamp Action Category Detail
2011-01-27 Added DEFINITION A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
2011-01-27 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2008-05-13 Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2008-05-12 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2007-07-27 Updated DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2007-06-27 Updated DEFINITION A membrane coat adaptor complex found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2002-11-27 Added DEFINITION An adaptor complex found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0030119 (AP-type membrane coat adaptor complex)
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