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GO:0030121 AP-1 adaptor complex

Term Information

ID GO:0030121
Name AP-1 adaptor complex
Ontology Cellular Component
Definition A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
PMID:10611976 PMID:21097499
GONUTS GO:0030121 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact HA1
exact HA1 clathrin adaptor

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000065 GO:0005794 Golgi apparatus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005907 HA1 clathrin adaptor CONSIDER GO:0030121

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030121:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030121. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030121 based on the entire annotation set Co-occurrence statistics for GO:0030121 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-01-27 Added DEFINITION A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
2011-01-27 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2008-05-13 Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2008-05-12 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2008-04-01 Updated RELATION is a GO:0030131 (clathrin adaptor complex)
2008-04-01 Updated RELATION is a GO:0044433 (cytoplasmic vesicle part)
2008-04-01 Updated RELATION is a GO:0044431 (Golgi apparatus part)
2008-04-01 Updated RELATION part of GO:0030130 (clathrin coat of trans-Golgi network vesicle)
2007-08-09 Added SYNONYM HA1
2007-08-09 Added SYNONYM HA1 clathrin adaptor
2007-08-09 Deleted SYNONYM HA1
2007-08-09 Deleted SYNONYM HA1 clathrin adaptor
2007-07-27 Updated DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2007-06-27 Updated DEFINITION A membrane coat adaptor complex that links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2005-08-10 Added SYNONYM HA1 clathrin adaptor
2004-04-19 Added SYNONYM HA1
2004-04-16 Deleted SYNONYM HA1
2002-11-27 Added DEFINITION An adaptor complex that links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2001-08-21 Added TERM AP-1 adaptor complex
2001-08-21 Added SYNONYM HA1

Term

Timestamp Action Category Detail
2001-08-21 Added TERM AP-1 adaptor complex

Definition/synonyms

Timestamp Action Category Detail
2011-01-27 Added DEFINITION A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
2011-01-27 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2008-05-13 Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2008-05-12 Deleted DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2007-08-09 Added SYNONYM HA1
2007-08-09 Added SYNONYM HA1 clathrin adaptor
2007-08-09 Deleted SYNONYM HA1
2007-08-09 Deleted SYNONYM HA1 clathrin adaptor
2007-07-27 Updated DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2007-06-27 Updated DEFINITION A membrane coat adaptor complex that links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2005-08-10 Added SYNONYM HA1 clathrin adaptor
2004-04-19 Added SYNONYM HA1
2004-04-16 Deleted SYNONYM HA1
2002-11-27 Added DEFINITION An adaptor complex that links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2001-08-21 Added SYNONYM HA1

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0030131 (clathrin adaptor complex)
2008-04-01 Updated RELATION is a GO:0044433 (cytoplasmic vesicle part)
2008-04-01 Updated RELATION is a GO:0044431 (Golgi apparatus part)
2008-04-01 Updated RELATION part of GO:0030130 (clathrin coat of trans-Golgi network vesicle)
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