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GO:0030057 desmosome

Term Information

ID GO:0030057
Name desmosome
Ontology Cellular Component
Definition A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.
GONUTS GO:0030057 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact macula adherens
exact spot desmosome

Cross-references

Database ID
InterPro IPR028432
InterPro IPR028434
UniProtKB-SubCell Desmosome
Wikipedia Desmosome

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030057:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030057. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030057 based on the entire annotation set Co-occurrence statistics for GO:0030057 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-05-27 Deleted RELATION part of GO:0043296 (apical junction complex)
2009-02-08 Added XREF Wikipedia:Desmosome
2008-11-27 Added RELATION is a GO:0070161 (anchoring junction)
2008-11-27 Deleted RELATION part of GO:0014704 (intercalated disc)
2008-11-27 Deleted DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2008-11-27 Added DEFINITION A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.
2008-05-13 Added DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2008-05-12 Deleted DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2008-04-01 Updated RELATION is a GO:0005911 (cell-cell junction)
2008-04-01 Updated RELATION part of GO:0014704 (intercalated disc)
2008-04-01 Updated RELATION part of GO:0043296 (apical junction complex)
2007-11-27 Updated DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2007-08-09 Added SYNONYM macula adherens
2007-08-09 Added SYNONYM spot desmosome
2007-08-09 Deleted SYNONYM macula adherens
2007-08-09 Deleted SYNONYM spot desmosome
2004-04-19 Added SYNONYM macula adherens
2004-04-19 Added SYNONYM spot desmosome
2004-04-16 Deleted SYNONYM macula adherens
2004-04-16 Deleted SYNONYM spot desmosome
2002-11-27 Updated DEFINITION Button-like point of intercellular contact through which the intermediate filaments of adjacent cells are connected indirectly.
2001-08-06 Added DEFINITION Button-like point of intercellular contact through whichthe intermediate filaments of adjacent cells are connected indirectly.
2001-06-21 Added SYNONYM macula adherens
2001-06-21 Added SYNONYM spot desmosome
2001-06-21 Added TERM desmosome

Term

Timestamp Action Category Detail
2001-06-21 Added TERM desmosome

Definition/synonyms

Timestamp Action Category Detail
2008-11-27 Deleted DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2008-11-27 Added DEFINITION A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.
2008-05-13 Added DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2008-05-12 Deleted DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2007-11-27 Updated DEFINITION A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress.
2007-08-09 Added SYNONYM macula adherens
2007-08-09 Added SYNONYM spot desmosome
2007-08-09 Deleted SYNONYM macula adherens
2007-08-09 Deleted SYNONYM spot desmosome
2004-04-19 Added SYNONYM macula adherens
2004-04-19 Added SYNONYM spot desmosome
2004-04-16 Deleted SYNONYM macula adherens
2004-04-16 Deleted SYNONYM spot desmosome
2002-11-27 Updated DEFINITION Button-like point of intercellular contact through which the intermediate filaments of adjacent cells are connected indirectly.
2001-08-06 Added DEFINITION Button-like point of intercellular contact through whichthe intermediate filaments of adjacent cells are connected indirectly.
2001-06-21 Added SYNONYM macula adherens
2001-06-21 Added SYNONYM spot desmosome

Relationships

Timestamp Action Category Detail
2010-05-27 Deleted RELATION part of GO:0043296 (apical junction complex)
2008-11-27 Added RELATION is a GO:0070161 (anchoring junction)
2008-11-27 Deleted RELATION part of GO:0014704 (intercalated disc)
2008-04-01 Updated RELATION is a GO:0005911 (cell-cell junction)
2008-04-01 Updated RELATION part of GO:0014704 (intercalated disc)
2008-04-01 Updated RELATION part of GO:0043296 (apical junction complex)

Cross-references

Timestamp Action Category Detail
2009-02-08 Added XREF Wikipedia:Desmosome
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