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GO:0030175 filopodium

Term Information

ID GO:0030175
Name filopodium
Ontology Cellular Component
Definition Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
Comment A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; may contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.
Secondary IDs GO:0030028
GONUTS GO:0030175 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462

Cross-references

Database ID
NIF_Subcellular sao-1046371754
UniProtKB-SubCell Filopodium
Wikipedia Filopodia

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030175:
Relationship To GO:0030175 Child Term Child Term Name
Part of GO:0031527 filopodium membrane
Part of GO:0032433 filopodium tip
Is a GO:1902737 dendritic filopodium

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0030175. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0030175 based on the entire annotation set Co-occurrence statistics for GO:0030175 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-03-07 Deleted DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2014-03-07 Added DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
2013-04-18 Updated SLIM goslim_pir
2011-11-26 Deleted SYNONYM microspike
2010-02-04 Added XREF NIF_Subcellular:sao-1046371754
2009-02-08 Added XREF Wikipedia:Filopodia
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2008-05-12 Deleted DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2008-04-01 Updated RELATION is a GO:0042995 (cell projection)
2007-08-09 Added SYNONYM microspike
2007-08-09 Deleted SYNONYM microspike
2004-09-02 Updated DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2004-04-19 Added SYNONYM microspike
2004-04-16 Deleted SYNONYM microspike
2003-06-26 Added SECONDARY GO:0030028 (microspike)
2003-06-26 Added SYNONYM microspike
2003-06-26 Updated DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2002-11-27 Added DEFINITION A very long microspike extended by the growth cone of a developing nerve cell axon; can be up to 50 micrometers long.
2001-08-30 Added TERM filopodium

Term

Timestamp Action Category Detail
2001-08-30 Added TERM filopodium

Definition/synonyms

Timestamp Action Category Detail
2014-03-07 Deleted DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2014-03-07 Added DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
2011-11-26 Deleted SYNONYM microspike
2008-05-13 Added DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2008-05-12 Deleted DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2007-08-09 Added SYNONYM microspike
2007-08-09 Deleted SYNONYM microspike
2004-09-02 Updated DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2004-04-19 Added SYNONYM microspike
2004-04-16 Deleted SYNONYM microspike
2003-06-26 Added SYNONYM microspike
2003-06-26 Updated DEFINITION Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
2002-11-27 Added DEFINITION A very long microspike extended by the growth cone of a developing nerve cell axon; can be up to 50 micrometers long.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0042995 (cell projection)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao-1046371754
2009-02-08 Added XREF Wikipedia:Filopodia

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2008-06-09 Added SLIM goslim_pir
2003-06-26 Added SECONDARY GO:0030028 (microspike)
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