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GO:0021680 cerebellar Purkinje cell layer development

The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.

Term Information

ID GO:0021680
Name cerebellar Purkinje cell layer development
Ontology Biological Process
Definition The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
Comment This term was added by GO_REF:0000021.

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Ancestor Table

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GO:0008150 biological_process
GO:0032502 developmental process
GO:0032501 multicellular organismal process
GO:0048856 anatomical structure development
GO:0007275 multicellular organismal development
GO:0048731 system development
GO:0048513 organ development
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0030902 hindbrain development
GO:0022037 metencephalon development
GO:0021549 cerebellum development
GO:0021695 cerebellar cortex development
GO:0021680 cerebellar Purkinje cell layer development

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0021691 cerebellar Purkinje cell layer maturation
P GO:0021692 cerebellar Purkinje cell layer morphogenesis

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
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Taxonomy
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Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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12ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-12-16-04-01-54
Terminal
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